In present study possible ameliorative efficacy of aqueous extract of bark of Alstonia scholaris (ASE) in cultured human lymphocytes against Bleomycin-induced cytogenetic alterations has been reported. Cultures were treated either alone with Alstonia scholaris aqueous bark extract (50μg/ml) or in combination with radiomimetic drug Bleomycin (15μg/ml). Positive implications about radioprotective...

The study utilized molecular-genetic, cytogenetic, and statistical analyzes methods. A cytogenetic molecular genetic analysis of the inhabitants villages Amangeldy, Belbulak, in whose territory warehouses unused pesticides are located, was carried out. Residents Basshi village, on which there no products disposal pesticides, were taken as control. Cytogenetic showed a high level chromosomal abe...

introduction: imatinib mesylate is a selective inhibitor of tk and is considered now to be the frontline therapeutic agent during the chronic phase of cml. we have evaluated the efficacy of it on children with chronic-phase of cml. patients and methods: in a clinical trial study over the past 3 years, 14 patients (8 females and 6 males, 2.5-14 years old) were admitted with a diagnosis of cml. s...

ObjectiveTo test the hypothesis that telomere shortening and/or loss are risk factors for infertility.DesignRetrospective analysis of status in patients with infertility using conventional cytogenetic data collected prospectively.SettingAcademic centers.Patient(s)Cytogenetic slides cultured peripheral lymphocytes from 50 undergoing fertility treatment and 150 healthy donors, including 100 donor...