Chemical—spectroscopic studies of the coupled bimuclear copper active site are presented which interpret the unique spectral features associated with oxyhemocyamim. These features are them used to generate a 'spectroscopically effective' model for this active site. First the met apo [Cu(II) — I and half met [Cu(II)Cu(I)J derivatives are spectro— scopically compared; they demonstrate that exogen...

Few studies have characterized or compared the pathologic features of bone marrow involvement by extranodal (EMZL), splenic (SMZL), and nodal marginal zone lymphoma (NMZL). We evaluated 45 bone marrow biopsy specimens from 39 patients with marginal zone lymphomas. As previously reported, bone marrow involvement was frequent (100%) in patients with SMZL. We also identified lymphoma involving bon...

Statins possess anti-inflammatory effects that may contribute to their ability to slow atherogenesis, whereas nitric oxide (NO) also influences inflammatory cell adhesion. This study aimed to determine whether a novel NO-donating pravastatin derivative, NCX 6550 [(1S-[1 ( S*, S*),2 ,6 ,8 -(R*),8a ]]-1,2,6,7,8,8a-hexahydro, ,6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-1-naphthalene-heptanoic ...