OBJECTIVES To determine contact allergies in patients with oral lichen planus and to monitor the effect of partial or complete replacement of amalgam fillings following a positive patch test reaction to ammoniated mercury, metallic mercury, or amalgam. DESIGN In group A (20 patients), the oral lesions were confined to areas in close contact with amalgam fillings. In group B (20 patients), the...

INTRODUCTION UVA phototherapy, acitretin and oral corticosteroids are currently the front-line treatment of disseminated cutaneous lichen planus. We studied the efficacy of narrow band UVB therapy in this indication. PATIENTS AND METHODS We retrospectively studied the dossiers of patients suffering from disseminated cutaneous lichen planus, treated with narrow band phototherapy in the Phototh...

OBJECTIVES Biologic therapy such as Etanercept, which is a tumor necrosis factor alpha (TNF-α) inhibitor, has been extensively used as election therapy in rheumatoid arthritis. The purpose of this case presentation was to inform about the possibility that lichen planus lesions could potentially become complicated by secondary infections in patients treated with Etanercept. Furthermore, we aimed...

CLP: cutaneous lichen planus DIF: direct immunofluorescence dsDNA: double-stranded DNA SLE: systemic lupus erythematosus OLP: oral lichen planus INTRODUCTION Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease that can involve oral mucosal membranes in up to 45% of patients. Oral presentation is commonly described as erythema involving multiple oral sites. Oral ulceration is ...

Lichen planus (LP) is a chronic inflammatory mucocutaneous disease of unknown aetiology with an estimated incidence 0.5%–4.0% having female preponderance at ratio 1.5:1. Oral lichen (OLP) commoner than the cutaneous form and tends to be more persistent refractory treatment. The prevalence oral in Indian population around 3% predilection. lesions occur 50%–70% patients planus. LP considered T-ce...

INTRODUCTION Contact with a jellyfish can cause a wide variety of conditions, ranging from cutaneous eruption to fatal cardiovascular and respiratory collapse. Cutaneous features can be both acute and chronic. We report a case of persistent lichen planus-like eruption in a young boy after a jellyfish sting, a hitherto unreported occurrence. CASE PRESENTATION A 15-year-old boy presented with m...

The purpose of this study was to determine whether keratinocytes in certain disease states such as cutaneous T-cell lymphoma and lichen planus, express HLA-DR antigens (corresponding to the murine I-E antigens) only or whether they are also capable of expressing HLA-DQ antigens (analogues of the murine I-A antigens). Cryostat sections from 11 biopsies from cutaneous T-cell lymphoma and from 11 ...

The present study intends to investigate COVID-19 by targeting their main proteins with 17 selected drugs used for treating Oral Lichen Planus (OLP) which is a chronic muco-cutaneous disorder. Read more at JCTRes.com