We describe a patient with primary cutaneous small-tomedium--sized CD4+ T-cell lymphoma, according to the most recent World Health Organization (WHO) classification of cutaneous lymphomas. This lymphoma, previously known as primary cutaneous small-to-medium-sized pleomorphic CD4+ T-cell lymphoma, has a low incidence and good prognosis. The interest in the case presented in this report derives f...

Rhinosporidiosis is a chronic, granulomatous, muco-cutaneous infection caused by Rhinosporidium seeberi . The non-contagious and sporadic in humans, affecting predominantly the mucous membrane of upper respiratory tract. It quite an uncommon condition seldom affects oral mucosa. clinical presentation this cavity can mimic many other conditions. Here, we report unique case recurrent rhinosporidi...

Hidradenitis suppurativa affects apocrine gland-bearing areas of skin and may produce perianal lesions clinically indistinguishable from the cutaneous manifestations of Crohn’s disease1, suggesting an association between the two diseases1–3. A recent histological study3 of hidradenitis suppurativa described epithelioid granulomas in 10 per cent of cases. Some of these patients had systemic gran...

GMF: granulomatous mycosis fungoides INF-a: interferon alfa MF: mycosis fungoides TCR: T-cell receptor G ranulomatous mycosis fungoides (GMF) is an unusual histologic subtype of cutaneous T-cell lymphoma. The diagnosis of GMF is usually established after observation of a granulomatous inflammatory reaction associated with a malignant lymphoid infiltrate. Epidermotropism, a clue to diagnosis in ...

We present the case of a patient who presented with signs and symptoms associated with a Klatskin tumor. After endoscopic retrograde cholangiopancreatography (ERCP) and biopsy, she was found instead to have granulomatous infiltration of the extrahepatic biliary tree consistent with biliary sarcoidosis. The patient was treated successfully with systemic corticosteroids and azathioprine. She late...

Interstitial granulomatous dermatitis (IGD) is a rare dermatosis of unknown cause with characteristic histopathological features and variable clinical expression.[1] It has been associated with systemic diseases which include rheumatoid arthritis, lupus erythematosus, autoimmune thyroiditis, carcinoma, infections and drug intake. It has recently been proposed that interstitial granulomatous der...

Besides being an uncommon clinicopathological entity, interstitial granulomatous dermatitis, also described as interstitial granulomatous dermatitis with arthritis (IGDA), has shown a wide spectrum of clinical manifestations, such as linear and erythematous lesions, papules, plaques and nodules. Histological features include dense dermal histiocytic infiltrate, usually in a palisade configurati...

Sporotrichosis is a subacute or chronic granulomatous mycosis caused by fungus of the Sporothrix schenckii complex. It is considered to be a rare condition in most parts of the world. It mostly causes cutaneous infection but can also cause multisystemic disease. Unlike most deep cutaneous mycoses which have a primary pulmonary focus, it is usually caused by direct inoculation of the fungus into...

A Granulomatous lesion in the skin is a common finding and cutaneous lymphoma, although less common, not rare entity. However few case reports exist of granulomatous harboring lymphoma. We present 72-year-old male, with no known co morbidities presenting painless erythematous papules nodules over forehead, trunk limbs since 10 days. The biopsy from showed granulomas along giant cells diffuse mo...