Background: The aim of the present study was to evaluate the utilization and diagnostic yields of CT pulmonary angiography (CTPA) using the Revised Geneva score and Wells’ criteria, in patients with suspected pulmonary embolism (PE).    Methods: One hundred and twelve adult patients underwent CTPA for suspected PE were participated in this study. The outcome was positive or neg...

BACKGROUND The use of computed tomography pulmonary angiography (CTPA) has been increased during the last decade. OBJECTIVES We studied the adherence to current diagnostic recommendations for evaluation of pulmonary embolism in a teaching hospital of Tehran University of Medical Sciences. PATIENTS AND METHODS The registered medical records (Wells scores and serum D-dimer level) of all patie...

AIMS To determine if computed tomographic pulmonary angiography (CTPA) was overemployed in the evaluation of hospitalized patients with suspected acute pulmonary embolism (PE). METHODS Data were gathered retrospectively on hospitalized patients (n=185) who had CTPA for suspected PE between June and August 2009 at our institution. RESULTS CTPA was done in 185 hospitalized patients to diagnos...

The putative carboxyl-terminal processing protease (CtpA) of Brucella suis 1330 is a member of a novel family of endoproteases involved in the maturation of proteins destined for the cell envelope. The B. suis CtpA protein shared up to 77% homology with CtpA proteins of other bacteria. A CtpA-deficient Brucella strain (1330DeltactpA), generated by allelic exchange, produced smaller colonies on ...

introduction: listeria monosytogenes is a gram-positive organism, frequently found in the environment and is responsible for serious food-born diseases such as perinatal infections, septicaemia and meningoencephalitis in humans and animals. materials & methods: distribution of the ctpa determinant among l. monosytogenes isolated from environmental and clinical samples was investigated using pcr...

PURPOSE OF REVIEW The purpose of this review is to focus on recent research that has addressed the relative merits of computed tomographic pulmonary angiography (CTPA) and ventilation perfusion (V/Q) scanning for the diagnosis of pulmonary embolism. RECENT FINDINGS Computed tomographic pulmonary angiography is the most sensitive test for the diagnosis of pulmonary embolism and its use has bee...

BACKGROUND Pulmonary embolism (PE) is associated with high morbidity and mortality. Effective intervention requires prompt diagnosis. Computed tomography pulmonary angiography (CTPA) is sensitive and specific for PE and is the investigation of choice. Inappropriate CTPA utilisation results in unnecessary high radiation exposure and is costly. State-of-the-art electronic radiology workflow can p...

The introduction of computed tomography pulmonary angiography (CTPA) has led to an increase in the incidence of pulmonary embolism (PE) diagnosis. However, the case fatality rate is lower and the mortality rates of PE have remained unchanged, suggesting a lower severity of illness. Specifically, the multiple-detector CTPA increased the rate of subsegmental filling defect reported in patients wi...

A suicide plasmid, pExp1-ctpA::tetM-recAec, employing recA from Escherichia coli and tetM as a selection marker, was used to generate ctpA knockout mutants in Mycoplasma mycoides subsp. capri through targeted gene disruption. Inclusion of E. coli recA greatly enhanced both the consistency and the recovery of mutants generated by homologous recombination.

BACKGROUND Invasive mold diseases (IMDs) of the lung remain a challenge for immunocompromised patients. Although timely diagnosis and treatment are crucial for the outcome of the infection, the poor sensitivity of microbiological techniques and the limited specificity of chest high-resolution computed tomography (HRCT) often delay definitive diagnosis of these infections. METHODS To explore t...