A microfluidic device with integrated sample preparation is introduced for the detection of cerebrospinal fluid rhinorrhea—a condition resulting in leakage of CSF from the nose due to head trauma. While CSF rhinorrhea is a serious condition, current state-of-the-art diagnostics are expensive or slow (MRI, CT scan or ELISA). We show the capability of a microfluidic immunoassay to accept and proc...

OBJECTIVE To determine the etiology and site of leak of cerebrospinal fluid (CSF) rhinorrhea and the surgical efficacy of Functional Endoscopic Sinus Surgery (FESS), in closing the defect of CSF leak by different graft materials. STUDY DESIGN Case series. PLACE AND DURATION OF STUDY Department of ENT-Head and Neck Surgery, Dow University of Health Sciences, Karachi, from September 2005 to D...

Abstract Introduction Cerebrospinal fluid (CSF) leak happens when there is an abnormal connection between the brain cavity inside and environment outside. It important to establish a good barrier tissue nose prevent cerebrospinal protect from exposure infection. which can be done either by endoscopic or non-endoscopic surgical repair. Patients methods The aim of this work evaluate effectiveness...

MR was useful in verifying CSF rhinorrhea following removal of an intracanalicular acoustic neurinoma via the occipital route in a 29-year-old man. MR accurately identified the location of the CSF leak.

We present the first report of Rathke’s cleft cyst presenting as CSF rhinorrhea following an asymptomatic period of fourteen years after the first surgery.Our patient, a fifty five year female presented to us with CSF rhinorrhea and two episodes of generalized tonic clonic seizures. She had been operated earlier in 1997 through right pterional craniotomy for decompression of cystic sellar supra...

An unusual case of spontaneous cerebrospinal fluid (CSF) rhinorrhea with a pneumocephalus is described in a middle-aged woman who presented with a watery nasal discharge for 1 week and headache, vomiting, and fever for 1 day. The neurological examination revealed meningeal signs and bilateral papilledema. The CSF picture suggested pyogenic meningitis, and computed tomography of the brain reveal...

BACKGROUND Traumatic brain injury represents a significant cause of mortality and permanent disability in the adult population. Posttraumatic CSF rhinorrhea is one of the conditions most strongly associated with severe brain injury. Knowledge on the natural history of the illness and the outcomes of patients with transcranial subfrontal approach for posttraumatic CSF rhinorrhea approach may hel...

Objective: To determine the frequency of early post-traumatic CSF (cerebrospinal fluid) rhinorrhea in patients with head trauma. Materials and Methods: A prospective study was conducted Department Neurosurgery, Jinnah Postgraduate Medical Centre, Karachi from 13th December 2019 to 12th 2020. This comprised 155 who had suffered All were followed for one week. If developed clear, watery discharge...

We report two children presenting with intermittent CSF rhinorrhea and recurrent meningitis. CT scan showed transethmoidal meningoencephalocele.