The amorphous aggregation of proteins is associated with many phenomena, ranging from the formation of protein wine haze to the development of cataract in the eye lens and the precipitation of recombinant proteins during their expression and purification. While much literature exists describing models for linear protein aggregation, such as amyloid fibril formation, there are few reports of mod...

PURPOSE To measure corneal and total optical aberrations in the normal and treated eye of a unilateral aphakic patient to (1) cross-validate techniques in an eye in which corneal and total aberrations should be almost identical (aphakic eye) and (2) compare the interactions of corneal and internal aberrations in the normal eye with those in the aphakic eye. SETTING Instituto de Optica, Consej...

Reversible corneal exposure cataracts have been observed in many rodents. The postulated mechanism has been one of transcorneal evaporation of water increasing the concentration of the aqueous and osmotically affecting the lens. In this experiment, changes in the colligative properties of hamster aqueous were measured as related to corneal exposure and the development of lens opacity. A rise of...

Omar Bagasra, Mohammed Alsayari, Rebecca Bullard-Dillard and Mohamed A Daw (1) Department of Biology, South Carolina Center for Biotechnology and Department Pathology, Microbiology and Immunology, School of Medicine, University of South Carolina. (2) Department of Biology, Claflin University (3) Department of Medical Microbiology and Immunology, Faculty of Medicine, Al-Fateh University, Tripoli...

In this paper synthesis and characterization of a bioactive calcium phosphate glass-ceramic is presented, synthesized using a facile method. The glass-ceramic samples are synthesized with heat treating the parent glass at appropriate temperatures, where different calcium phosphate crystalline phases are grown in the parent glass samples during the heat treatment. The amounts of elements a...

An exoteric geometric mechanics model of ocular accommodation is detailed to elucidate the main ideas of various ongoing modeling efforts. The present study derives solutions for the stretched state of the ocular lens as it might appear during accommodation by using simple geometric arguments and a volume constraint, rather than the more mathematically intensive theory of elasticity. Results sh...

The in vivo spherical aberration of the lenses of 26 subjects was estimated from the measured total aberration of the eye and that predicted from the measured shape of the anterior corneal surface. Since it was only possible to estimate the aberration contribution from the posterior corneal surface, its value led to an uncertainty in the final aberration level of the lens. For all the subjects ...