Chronic rhinosinusitis (CRS) is a common disorder characterized by mucosal inflammation of the nose and paranasal sinuses with sinonasal symptoms persisting for greater than 12 weeks. The etiology of CRS is incompletely understood. Current understanding supports inflammation, rather than infection, as the dominant etiologic factor. CRS significantly impacts patients' quality of life and health ...

Chronic rhinosinusitis (CRS) is a relevant and prevalent medical condition in Germany, Europe and the world. If analysed in detail, the prevalence of CRS shows regional and temporary variety. In this review, currently available data regarding the prevalence of CRS is therefore sorted by country and/or region, time point of data collection and the CRS-definition employed. Risk factors like smoki...

background and objective: chronic rhinosinusitis (crs) is one of the most common chronic diseases. in the past decades, there has been an increase in fungal infections of sinuses and fungal rhinosinusitis (frs) has been diagnosed more frequently. knowing the fungal flora and its prevalence in crs patients will allow a better understanding of this disease, permitting a correct diagnosis, treatme...

Caudal regression syndrome (CRS) is a rare congenital disorder in which lumbosacral anomalies are combined with anorectal and urogenital malformations. However, the molecular mechanisms of human CRS are not yet known. Trauma, nutritional problems, toxic agents, and genetics are suggested in the etiology of CRS. To the best of our knowledge, linkage studies of families affected exclusively by CR...

OBJECTIVES/HYPOTHESIS Patients with chronic rhinosinusitis (CRS) who experience minimal reductions in quality of life (QoL) may present for treatment despite QoL scores comparable to controls without CRS. This study seeks to identify cofactors influencing patients with CRS and low 22-item Sinonasal Outcome Test (SNOT-22) scores to seek care. STUDY DESIGN Prospective, multicenter, observationa...

BACKGROUND Chronic rhinosinusitis (CRS) is a common disease in the United States. There are a significant number of patients with CRS who are refractory to standard medical and surgical therapy. Many of these patients also have comorbid allergic rhinitis (AR) and asthma, although the underlying pathophysiology that connects these three conditions remains unclear. OBJECTIVE The goal of this ar...

OBJECTIVE The chemotherapy response score (CRS) system based on histopathological examination has been recently proposed for tubo-ovarian high-grade serous carcinoma (HGSC) to assess response to neoadjuvant chemotherapy (NAC). This study was aimed at validating the CRS system in an external cohort of tubo-ovarian HGSC patients. METHODS This study included 110 tubo-ovarian HGSC patients who un...

The standard treatment for advanced ovarian cancer consists in complete cytoreductive surgery (CRS) and intravenous combination chemotherapy with a platinum compound and a taxane. Although response rates to initial therapy are high, many patients will recur and die of peritoneal carcinomatosis. The addition of Hyperthermic IntraPEritoneal Chemotherapy (HIPEC) to the standard therapy aims at inc...

Natural disasters can severely impact transportation networks. In the hours and days following a major flooding event, knowing the location and extent of the damage is crucial for incident managers for a number of reasons: it allows for emergency vehicle access to affected areas; it facilitates the efficient rerouting of traffic; it raises the quality and reduces the cost of repairs; and it all...

In the recent years, heterogeneous network (HetNet) is used to improve the spectral efficiency and network capacity of Long Term Evolution-Advanced (LTE-A). Although, it has huge traffic congestion due to numerous numbers of mobile users and data terminals, leads to problems of cooperation between Macro-cell and Pico-cells. One of the major interference sources in LTE-A is Common Reference Sign...