Motor cortex stimulation (MCS) is useful to treat patients with neuropathic pain syndromes, unresponsive to medical treatment. Complex regional pain syndrome (CRPS) is a segmentary disease treated successfully by spinal cord stimulation (SCS). However, CRPS often affects large body segments difficult to cover by SCS. This study analyzed the MCS efficacy in patients with CRPS affecting them. Fiv...

OBJECTIVES Recent studies have confirmed the contribution of the central nervous system (CNS) to the pathogenesis of Complex Regional Pain Syndrome (CRPS), because animal models of neuropathic pain syndromes demonstrate an overexpression of N-methyl-D-aspartate-receptors in the CNS. The aim of this work was to study the influence of a central acting drug-the N-methyl-D-aspartate receptor antago...

OBJECTIVE To successfully treat a patient with complex regional pain syndrome, refractory to standard therapy, to enable a rapid and full return to professional duties. SETTING This case report describes the rapid resolution of an unusual presentation of complex regional pain syndrome type I after four days of treatment with a continuous sciatic peripheral nerve block and a concomitant parent...

Sympathectomy may provide temporary pain relief, but after a few weeks to months it loses its effect. Sympathectomy and the application of Chemical Sympathectomy (neurolytic agents e.g., phenol, alcohol, etc.) should be limited to patients with life expectancies measured in weeks or months e.g., cancer patients. Chemical Sympathectomy (e.g., alcohol, phenol or hypertonic saline nerve blocks) ai...

Although the goal of medicine is to cure disease, effective treatment of the symptoms that the patient notices requires that the clinician identify their underlying cause – namely the diagnosis. Without a diagnosis, clinicians can only palliate the symptoms and hope that the actual disease resolves on its own. The 20th century brought great advances in understanding disease pathophysiology. For...

Complex regional pain syndrome (CRPS) is a painful condition that most often affects limbs. Upper extremity is affected more frequently than lower extremity. The character of the pain is continuing, spontaneous, usually burning and unexpectedly severe pain considering any inciting cause. Pain does not follow the anatomical distribution of a peripheral nerve. Diagnosis is still clinical. The pre...

The term Complex Regional Pain Syndrome (CRPS) is a pain disorder in which the pain is disproportionate to the initial inciting injury. The disorder is complex because it involves multiple organ systems with abnormal blood flow, sweating abnormalities, trophic changes, and fine motor impairment. The pain distribution tends to be regional (not dermatomal), and is not limited to the area initiall...

We report a 66-year-old woman with complex regional pain syndrome (CRPS) 1 treated with combined medical and active physical therapy. She was diagnosed with CRPS 1 following partial shoulder prosthesis due to proximal humerus fracture. Despite continuous medication and physical therapy, there was no improvement in her pain and functional outcome. Her overall pain was decresed by stellate gangli...