In this study, a chitosan substrate was modified by simulated body fluid (SBF) treatment, in which the effect of the chosen crosslinking agent was investigated. Two crosslinking agents, glutaraldehyde (GA) and sodium tripolyphosphate (TPP), were used before the SBF process. By using TPP as the crosslinking agent, the Ca/P ratio and the degree of crystallinity were very close to the natural bone...

in present research work, homogeneous anion exchange membranes based on polysulfone (qapsfs) were prepared via chloromethylation, amination and alkalization. in amination step, trimethylamine and n,n,n',n'-tetramethyl-1,6-hexanediamine were used as amination and crosslinking agents, respectively. the chloromethylated polysulfone was characterized by 1hnmr spectroscopy and chloromethylation degr...

AbstractIn the last step of desolvation method for preparation of albumin nanoparticles, glutaraldehyde (GA) is added to stabilize the newly formed nanoparticles. Due to undesirable effects of GA, the objective of this study was to evaluate alternative methods of crosslinking including ultraviolet (UV) irradiation, adding of glucose and combination of both methods. The nanoparticles were prepar...

Chemical crosslinking in combination with Fourier transform ion cyclotron resonance mass spectrometry (FTICR MS) has significant potential for studying protein structures and protein-protein interactions. Previously, cisplatin has been shown to be a crosslinker and crosslinks multiple methionine (Met) residues in apo-calmodulin (apo-CaM). However, the inter-residue distances obtained from nucle...

München vorgelegt von Katrin Hahlen aus Köln 2004 Ehrenwörtliche Versicherung Diese Dissertation wurde selbständig und ohne unerlaubte Hilfsmittel angefertigt. "Testing kinesin's flexibility by crosslinking: Which domains need to be mobile to allow mobility?" "Testing kinesin's flexibility by crosslinking: Which domains need to be mobile to allow mobility?" "The role of the neck in fast kinesin...

Integrally-skinned asymmetric Polyetherimide/Poly (vinyl alcohol) (PEI/PVA) hollow fber membranes for pervaporation dehydration were fabricated by non-solvent induced phase inversion. PVA inside the PEI matrix could be crosslinked to provide membrane performance stability during long term operation. The effects of different PEI/PVA blend ratio, external coagulant type and...

Formaldehyde crosslinking has been widely used to study binding of specific proteins to DNA elements in intact cells. However, previous studies have not determined if this crosslinker preserves the bona fide pattern of DNA binding. Here we show that formaldehyde crosslinking of Drosophila embryos maps an interaction of the transcription factor Zeste to a known target element in the Ultrabithora...

PURPOSE To evaluate the efficacy of corneal collagen crosslinking for progressive keratoconus in paediatric patients. METHODS This prospective study included 25 eyes of 18 patients (aged 18 years or younger) who underwent collagen crosslinking performed using riboflavin and ultraviolet-A irradiation (370 nm, 3 mW/cm2, 30 min). RESULTS The mean patient age was 14.3±2.4 years (range 8-17) and...