In this paper the authors deal with the scheduling of inbound and outbound trucks to the available inbound and outbound doors at a cross dock facility. They assume that all trucks served at the facility need to meet several deadlines for deliveries and pick-ups and thus request a departure time window from the facility, penalizing the facility operator, on a unit of time basis, if that deadline...

We study a cross-dock operator’s truck scheduling problem at inbound doors in case of unknown truck arrival times. Due to uncertainty of truck arrivals, a scheduling strategy is subject to variations in costs of serving the trucks. A cost-stable scheduling strategy is defined as a schedule with low variation levels. In this paper, we analyze the cross-dock operator’s problem of determining a co...

Dilated cardiomyopathy is a disease of left ventricular dysfunction accompanied by impairment of the β1-adrenergic receptor (β1-AR) signal cascade. The disturbed β1-AR function may be based on an elevated sympathetic tone observed in patients with heart failure. Prolonged adrenergic stimulation may induce metabolic and electrophysiological disturbances in the myocardium, resulting in tachyarrhy...

In this research, a truck scheduling problem for cross-docking system with multiple receiving and shipping docks is studied. Until recently, single-dock problems are studied mostly. This research focused on the multiple-dock problems. The objective of to determine best docking sequences inbound outbound trucks docks, respectively, which minimize maximal completion time. We propose new hybrid ge...

SUMMARY Mutations in the Drosophila gene dreadlocks (dock) disrupt photoreceptor cell (R cell) axon guidance and targeting. Genetic mosaic analysis and cell-type-specific expression of dock transgenes demonstrate dock is required in R cells for proper innervation. Dock protein contains one SH2 and three SH3 domains, implicating it in tyrosine kinase signaling, and is highly related to the human...