Abstract Background The recently developed TIGER endoscopy score was established to reliably describe disease severity as it can be utilized for both Ulcerative Colitis (UC) and Crohn’s (CD) patients.1The aim of this prospective study assess the score’s ability predict UC CD patient outcomes including biologic steroid use. Methods A cohort 78 patients with (n=40) (n=38) were included in a 52-we...

crohn’s disease is an inflammatory bowel disease (ibd), characterized by chronic intestinal inflammation that causes the loss of immune tolerance leading to bizarre inflammatory signals and disruption of mucosal barriers. environmental triggers and interaction of genetic determinants also play an indispensible role. in this case report, we present a pre-pubertal girl with intermittent and refra...

background: there is evidence that pulmonary function abnormalities are present in patients with inflammatory bowel disease (ibd). the aim of this case-control study was to assess the frequency of pulmonary dysfunction in patients with ibd. materials and methods: pulmonary function of 37 patients with ibd (8 with cd and 29 with uc) without any known pulmonary disease was tested by body-box plet...

Derek Jewell Professor of Gastroenterology, Gastroenterology Unit, Radcliffe Infirmary, Oxford, OX2 6HE, UK. Tel: +44 (0) 1865 224829; Fax: +44 (0) 1865 790792; E-mail: [email protected] The genetics of inflammatory bowel disease (IBD) is an area of enormous topical interest. Crohn’s disease is one of the first polygenic diseases in which a susceptibility gene (NOD2 ) ...

Ulcerative colitis (UC) is a chronic relapsing inflammatory bowel disease (IBD). The pathogenesis of IBD is complex and so far not fully understood. The long-term clinical outcome of UC is hard to predict. Some clinical phenotypes of UC may to some extent predict the severity of the disease, but the clinical impact of these predictors is minor. . The new immunomolecular understanding of the pat...