نتایج جستجو برای: critical pathways
تعداد نتایج: 704246 فیلتر نتایج به سال:
potent induction of fetal hemoglobin (hbf) production results in alleviating the complications of β-thalassemia and sickle cell disease (scd). hbf inducer agents can trigger several molecular signaling pathways critical for erythropoiesis. janus kinase/signal transducer and activator of transcription (jak/stat), mitogen activated protein kinas (mapk) and phosphoinositide 3-kinase (pi3k) are con...
The notions of the critical path of events and critical time of an event are key concepts in analyzing the performance of a parallel discrete event simulation. The highest critical time of any event in a simulation is a lower bound on the time it takes to execute a simulation using any conservative simulation mechanism, and is also a lower bound on the time taken by some optimistic methods. How...
We study the problem of the manager of a project consisting of two sub-projects or tasks which are outsourced to different subcontractors. The project manager earns more revenue from the project if it is completed faster, but he cannot observe how hard subcontractors work, only the stochastic duration of their tasks. We derive the optimal linear incentive contracts to offer to the subcontractor...
The rotary pipeline processor is a new architecture for superscalar computing. It is based on a simple and regular pipeline structure which can support several ALUs for efficient dispatching of multiple instructions. Register values flow around a rotary pipeline, constrained by local data dependencies. During normal operation the control circuits are not on the critical path and performance is ...
The classical PERT approach uses the path with the largest expected duration as the critical path to estimate the probability of completing a network by a given deadline. However, in general, such a path is not the most critical path (MCP) and does not have the smallest estimate for the probability of completion time. The main idea of this paper is derived from the domination structure between ...
In this paper, we propose a new approach to critical path analysis in a project network whose activity times are uncertain. The uncertain parameters in the project network are represented by fuzzy numbers. We use fuzzy arithmetic and a fuzzy ranking method to determine the fuzzy critical path of the project network without converting the fuzzy activity times to classical numbers. The proposed m...
Effective and detailed planning of large-scale, complex construction projects is of great importance to fulfilling project cost and time objectives. At Tsinghua University of China and The Hong Kong Polytechnic University, the four dimensional-computer aided design (4D construction operations simulation methodology have been researched for years respectively, resulting in innovative, in constru...
The development of robust desulfurizers and new reforming catalysts is a critical path for the use of jet fuels in powering the commercial growth of fuel cell systems for air and military applications. The presence of high concentrations of sulfur-containing organic compounds leads to rapid deactivation of traditional reforming catalysts, and removal of the sulfur components from the fuel throu...
A new flip-flop design using a double-pulsed static latch is presented. The flip-flop has only a single stage of logic in the critical path and as a result is up to three times faster than the fastest previously known flip-flops, while consuming approximately the same energy as the lowestpower flip-flops. The flip-flop has asymmetric timing properties which make it a good match to skewed logic ...
High-performance cache architectures always pull up the bitlines in all cache subarrays to hide the bitline charging latency prior to a cache access. Unfortunately, such architectures lead to significant bitline discharge in unaccessed subarrays in nanoscale CMOS caches and waste power. Recent proposals advocate bitline isolation to reduce bitline discharge in unaccessed subarrays by turning of...
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