Cases of membranous nephropathy (MN) with crescent formation, in the absence of lupus, hepatitis B virus infection, anti-glomerular basement membrane (GBM) nephritis, or antineutrophil cytoplasmic antibody (ANCA), are on record. Clinical presentation and treatment outcomes in these patients are unclear. All patients with biopsy-proven MN diagnosed between years 2008 and 2014 and followed up wer...

We try to improve the accuracy of eccentric photorefraction by taking more information into account than just the size and tilt of the crescent. Based on Gaussian optics and the assumption of an isotropic scattering retina, a theoretical analysis of the light-intensity distribution in the pupils of astigmatic eyes is presented. The method is applied to different photorefractor setups (point lig...

?tv, *s Sreat value to every medical practitioner. The note is divided into two sections: I. The effect of plasmoquine on the viability of crescents. II. The effect of plasmoquine on the development ?f crescents. In the first section the literature of the subject is reviewed and special attention is called to the suggestions of Miihlens and Cordes that mass treatment with plasmoquine may be eff...

In patients with glomerulonephritis widespread crescents are associated with a poor prognosis. Crescent formation appears to depend on the migration of mononuclear cells into Bowman's space, and therefore the interaction between leukocytes and glomerular endothelium may be a critical event in the genesis of crescents. We performed the present study to determine the effects of mouse monoclonal a...

Crescents are morphologic manifestations of severe glomerular injury. Several chemokines and their receptors have been demonstrated to be involved in animal models of crescentic glomerulonephritis (cGN) and are potential targets for therapeutic interventions. Therefore, the expression of monocyte chemoattractant protein-1 (MCP-1), its receptor chemokine receptor 2B (CCR2B), and CCR5 in human cG...

The cytoplasmic assembly of vaccinia virus begins with the transformation of a two-membraned cisterna derived from the intermediate compartment between the endoplasmic reticulum and the Golgi complex. This cisterna develops into a viral crescent which eventually forms a spherical immature virus (IV) that matures into the intracellular mature virus (IMV). Using immunoelectron microscopy, we dete...

BACKGROUND Crescent formation generally reflects severe glomerular injury. There is sparse literature on post-infectious glomerulonephritis (PIGN) with crescents in adults. This retrospective study looked at nine such cases to see if there is a correlation between the severity of presentation, steroid treatment, histological severity and outcome. METHODS Biopsy reports of all the adults who u...