background: immunotherapy is the only specific treatment for scorpion envenomation. in the present study, the protective effects of polyvalent antivenom against histopathological complications in kidneys and marker changes (bun and creatinine) induced by mesobuthus eupeus (me) scorpion venom was investigated in anesthetized rabbits. methods: twenty four rabbits were randomized into four groups:...

Introduction: In this study, we evaluated the antidiabetic and antidiabetogenic effect of saffron against diabetes induced by artificial dye tartrazine on normal male rats. Methods: Dried saffron was macerated for 12 hours in distilled water before usage and crude extract was used to treat male rats. Rats were divided into 5 groups consisted of 6 rats and treatment was performed daily a...

introduction the concentration of substances, including urea, creatinine, and uric acid, can be used as an index to measure toxic uremic solutes in the blood during dialysis and interdialytic intervals. the on-line monitoring of toxin concentration allows for the clearance measurement of some low-molecular-weight solutes at any time during hemodialysis.the aim of this study was to determine the...

background: all the three nitric oxide synthase (nos) isoforms are presented in the kidney. some data provided evidences that enos activity leads to restoration of renal function after injury, but activation of inos aggravates renal failure. in the present study, we investigated that whether in gentamicin-induced renal failure selective inos blockade is beneficial. materials and methods: four g...

LBM should be taken into account (1 ). However, as shown here and previously (3 ), the contribution of LBM to variations in serum creatinine is small. The group of subjects studied were all females, and this may account for the low contribution. However, their LBM covered a wide range (23.0–53.7 kg), and thus it is likely that the findings here would be widely applicable. These results suggest ...

background assessment of glomerular filtration rate (gfr) by common creatinine-based methods is potentially inaccurate in patients with cirrhosis. cirrhotic patients have several underlying conditions that contribute to falsely low serum creatinine concentrations, even in the presence of moderate to severe renal impairment. therefore creatinine-based methods usually overestimate true gfr in the...

1. Creatinine metabolism was studied in nine patients with severe chronic renal failure who were nevertheless in a nearly steady state with respect to their creatinine pool. Labelled creatinine was injected intravenously and the specific radioactivity of creatinine in urine was measured during the ensuing 5-7 days. 2. In each patient, the decline in specific radioactivity with time was a single...