Cotrimoxazole (trimethoprim-sulfamethoxazole) is routinely provided to individuals with AIDS in the United States and Europe for prevention of opportunistic infections, especially Pneumocystis jerovici pneumonia. In Africa, it has been shown to reduce human immunodeficiency virus (HIV)associated mortality and morbidity, including reductions in the incidence of malaria, pneumonia, diarrhea, and ...

BACKGROUND Cotrimoxazole prophylaxis has an antimalarial effect which could have an additional protective effect against malaria in HIV-infected children on antiretroviral therapy (ART). We measured the incidence and associated factors of malaria in HIV-infected children on ART and/or cotrimoxazole in Abidjan, Côte d'Ivoire. METHODS All HIV-infected children <16 years, followed-up in the IeDE...

BACKGROUND Q fever is a zoonosis caused by Coxiella burnetii. During pregnancy, it may result in obstetric complications, such as spontaneous abortion, intrauterine growth retardation, intrauterine fetal death, and premature delivery. Pregnant women are exposed to the risk of chronic Q fever. METHODS We included 53 pregnant women who received a diagnosis of Q fever. We compared the incidence ...

determination of drug resistance rate, as a new major problem in patients with typhoid fever is inevitable for treatment of the disease. in a cross-sectional study, during march 1994 till february 1995, a total of 39 patients with typhoid fever admitted to dept. of infections diseases, emam khomeini hospital, and were examined for the rate of resistance to routine drugs usually used for treatme...

OBJECTIVES To assess the feasibility and effectiveness of voluntary counselling, HIV testing and adjunctive cotrimoxazole in reducing mortality in a cohort of tuberculosis (TB) patients registered under routine programme conditions in a rural district of Malawi. DESIGN 'Before' and 'after' cohort study using historical controls. METHODS Between 1 July 1999 and 30 June 2000 all TB patients w...

The deteriorating behaviour of 1xxx aluminium series in different concentrations Cotrimoxazole drugs was investigated 0.5M HCl using linear potentio-dynamic polarization techniques. inhibition action elucidated on the surface. result test shows that increase corrosion rates is directly proportional to mass concentration acidic environment. inhibited samples had lower current density and higher ...

BACKGROUND Data on the population effectiveness of cotrimoxazole prophylaxis and antiretroviral therapy (ART) in human immunodeficiency virus (HIV)-infected African children are few. METHODS A total of 534 Zambian children with HIV infection were randomized to receive daily cotrimoxazole prophylaxis or placebo in the Children with HIV Antibiotic Prophylaxis trial. Following trial closure, chi...