Decision makers are frequently faced with the question of how realistic are cost-effectiveness models. Overall survival (OS) is a desired clinical trial and health technology assessment endpoint but frequently unrealistic or elusive at the point of new drugs financing decision. We aim to compare the overall survival from lenalidomide treatment in relapsed/refractory multiple myeloma (rrMM) pati...

This paper applies modeling in Alloy and verification with the Alloy Analyzer to the well-known Chord protocol. The results include the first rigorous proof that the join-only case is correct, and many counterexamples showing that the full protocol is not correct. The paper also explains the methods so they can be applied to other protocols, justifies their costeffectiveness in protocol design,...

S18 ENDOSCOPIC ULTRASOUND / VOLUME 6 / SUPPLEMENT 1 / AUGUST 2017 and adenocarcinoma was detected. None of the lesions had mucinous morphology. There were no periprocedural complications. Conclusion: EUS is an effective modality to detect occult primary in patients with CUPS with suspected pancreaticobiliary origin. Larger studies assessing its costeffectiveness and identifying positive predict...

Modelling A decision tree model was created to capture the central issues in acute DVT treatment and to examine the costeffectiveness of fondaparinux for DVT therapy compared with enoxaparin. The model was based on various assumptions on efficacy, drug dosing and costs, which were all reported in the current study but are too numerous to be reported here. However, the authors reported that thei...

Objectives This three-year, international, multicentre, longitudinal, observational, cost-effectiveness study named RaDiCEA (RareDisease &Cost-EffectivenessAnalysis) will assess the economic evaluation (cost of illness COI and costeffectiveness analysis CEA) of innovative therapies (i.e., anti IL-1 agents), quality of life (QoL) and effects of the prevention of otherwise irreversible central ne...

Background Cardiac MRI (CMR) T2 mapping is a proven method for myocardial edema detection. However, the current approach requires multiple breath-holds and can take nearly 10-15 minutes to complete. Faster acquisitions could potentially improve patient comfort and costeffectiveness of CMR exams. the objecttive of this study is to develop and test a free-breathing, three-dimensional, cardiac MR ...

S18 ENDOSCOPIC ULTRASOUND / VOLUME 6 / SUPPLEMENT 1 / AUGUST 2017 and adenocarcinoma was detected. None of the lesions had mucinous morphology. There were no periprocedural complications. Conclusion: EUS is an effective modality to detect occult primary in patients with CUPS with suspected pancreaticobiliary origin. Larger studies assessing its costeffectiveness and identifying positive predict...

S18 ENDOSCOPIC ULTRASOUND / VOLUME 6 / SUPPLEMENT 1 / AUGUST 2017 and adenocarcinoma was detected. None of the lesions had mucinous morphology. There were no periprocedural complications. Conclusion: EUS is an effective modality to detect occult primary in patients with CUPS with suspected pancreaticobiliary origin. Larger studies assessing its costeffectiveness and identifying positive predict...

Methods: Ammonia concentrations in farrowing, nursery, finisher, and gestating barns were monitored for 8 weeks using both the pHydrionTM test strips and the DraegerTM unit. The ammonia measurements were compared using bivariate correlation analysis. Average ammonia concentrations in each barn type were compared using an ANOVA. The precision and costeffectiveness of each assay were demonstrated...