Background: Adrenal insufficiency, a well recognised complication of treatment with oral corticosteroids, has been described in association with inhaled corticosteroid use in over 60 case reports. The risk of adrenal insufficiency in people prescribed an oral or inhaled corticosteroid in the general population is not known. A study was undertaken to quantify the association between adrenal insu...

BACKGROUND Adrenal insufficiency, a well recognised complication of treatment with oral corticosteroids, has been described in association with inhaled corticosteroid use in over 60 case reports. The risk of adrenal insufficiency in people prescribed an oral or inhaled corticosteroid in the general population is not known. A study was undertaken to quantify the association between adrenal insuf...

These experiments were designed to test whether the pattern of change in plasma corticosteroid or the total corticosteroid dose is important in determining the degree of inhibition of adrenocorticotropic hormone (ACTH) responses to stress by corticosteroid intermediate-delayed feedback. Five conscious dogs were studied. The ACTH response to induced hypoglycemia was measured after no prior corti...

N Engl J Med 2003;348:727-34. Copyright © 2003 Massachusetts Medical Society. n increase in tissue corticosteroid levels during acute illness is an important protective response. Many diseases and their treatments interfere with the normal corticosteroid response to illness and thus induce tissue corticosteroid insufficiency. In this article, we review the physiology of the corticosteroid respo...

Because of their anti-inflammatory activity, corticosteroids generally mask the clinical signs of a contact dermatitis to a corticosteroid preparation. The lesions usually present as chronic dermatitis, and the patients mostly report not exacerbations but failures to respond to corticosteroid therapy. Moreover, masking also occurs with patch-test reactions obtained with corticosteroid preparati...

Introduction: The objective of this study was to describe the modalities responses observed following realization a bolus methylprednisolone in children treated for nephrotic syndrome pediatric nephrology unit Abidjan order assess need its our practice. Methods: we carried out descriptive and analytical cross-sectional patients followed up having benefited from administration 3 boluses at dosag...

background: osteoporosis is a preventable and treatable disorder, reported with higher prevalence patients with ulcerative colitis but their relationship is controversial. osteoporosis in these patients may be attributes to corticosteroid use, malnutrition and reduced intake of calcium and vitamin d, lower levels of sex hormones, chronic inflammation and inflammatory cytokines. the aim of study...