Background. It has been suggested that recurring coronary artery spasm may lead to the development of fixed atherosclerotic coronary obstructions. Methods and Results. We studied 10 patients with typical Prinzmetal's variant angina in whom the disease remained active for years and in whom occlusive coronary spasm occurred reproducibly at the same arterial site during repeat coronary arteriograp...

36:97–100 5. Briard C, Corat P, Commin P, Chollet A, Menasche P, Echter E: Coronary artery spasm during non-cardiac surgical procedure. Anaesthesia 1983; 38:467–70 6. Buffington CW, Ivey TD: Coronary artery spasm during general anesthesia. ANESTHESIOLOGY 1981; 55:466–9 7. Skarvan K, Graedel E, Hasse J, Stulz P, Pfister M: Coronary artery spasms after coronary bypass surgery. ANESTHESIOLOGY 1984...

Effects of leukotriene (LT) C4 and LTD4 on coronary artery spasm in atherosclerotic miniature pigs were examined angiographically. Endothelial balloon denudation of the left circumflex coronary artery was performed in 15 Göttingen miniature pigs; 11 were fed a 2% cholesterol diet and four were fed a regular diet for 3 months. Three months after this denudation, the area of the coronary artery w...

Three patients had hypertrophic obstructive cardiomyopathy and coronary artery spasm. The clinical diagnosis of hypertrophic obstructive cardiomyopathy, in all patients, was confirmed by echocardiography and angiography. Significant spasm of the right coronary artery was demonstrated in each patient by selective coronary arteriography. One patient had atherosclerotic obstructive three vessel di...

Dobutamine stress echocardiography is widely performed as a useful diagnostic tool in patients with known or suspected coronary artery disease. Dobutamine induced myocardial ischaemia is frequently associated with ST segment depression. ST segment elevation is uncommon and is almost always associated with prior myocardial infarction or transient total coronary occlusion. Dobutamine induced ST s...

dobutamine stress echocardiography (dse) has been widely used as a diagnostic and prognostic modality in the management of stress. dse is associated with limited complications and adverse effects on the health of patients. in this case report, we described a 42-year-old female patient with dobutamine-induced coronary artery spasm with history of exertional dyspnea, which had deteriorated recent...

Sir, I read with interest the article on Prinzmetal's angina and coronary artery spasm by Huckell and coworkers (Br Heart J 1981; 45: 649-55). The authors mentioned the association of mitral valve prolapse in eight of their 18 patients with Prinzmetal's angina, and wondered whether this finding was causative or coincidental, or whether patients with mitral prolapse were more prone to develop co...

We injected acetylcholine (ACh), the neurotransmitter of the parasympathetic nervous system, into the coronary arteries of 28 patients with variant angina. Injection of 10 to 80 micrograms ACh into the coronary artery responsible for the attack induced spasm together with chest pain and ST segment elevation or depression on the electrocardiogram in 30 of the 32 arteries of the 25 of the 27 pati...

A 50-year-old man suffering from recurrent chest pain accompanied by transient ST-segment elevation developed spasm of the left anterior descending coronary artery after receiving ergonovine maleate. During spontaneous chest pain, thermodilution coronary sinus blood flow fell from 96 ml/min to 46 ml/min, while the coronary sinsu arteriovenous oxygen difference widened from 9.82 volumes percent ...

Spasm of the radial artery is the most important cause of failure to perform coronary angiography via the transradial approach. Spasmolytic cocktail may prevent radial artery spasm but is relatively contraindicated in patients with aortic stenosis or diminished left ventricular function. In this case report we describe a recently published technique to overcome severe radial spasm during transr...