Background: Because of stress oxidative side effect of MTX on reproductive system, current study was aimed to evaluate protective effects of cornus mas fruit extract (CMFE) in mice treated with methotrexate (MTX). Materials and Methods: 48 young mature male mice were classified in 4 groups. Control group received only normal saline orally (0.2 ml/day), and the second group was administered MTX ...

Current study was aimed to evaluating protective effects of cornus mas fruit extract (CMFE) in mice treated with methotrexate (MTX). For this purpose, 48 young mature male mice were divided into 6 groups. Control group received only normal saline (0.1 mL per day, intraperitoneally), and the second group was administered MTX (20 mg kg(-1) per week, intraperitoneally). The third, fourth and fifth...

Background. The plant Cornus mas L. (cornelian cherry) is traditionally used as an antidiabetic supplement; however, there is no related clinical trial. In this study, we evaluated the effects of the fruit extract of this plant on biomarkers of glycemic control in adult patients with type 2 diabetes. Methods. Sixty patients with type 2 diabetes were randomly assigned to two groups to receive ei...

Cornus mas L. (Cornaceae family) known as the Asiatic and European cornelian cherry is a species of dogwood native to Southwest Asia and Southern Europe. Cornelian cherry is an obviously growing dogwood species in Arasbaran (East Azerbaijan, Iran). It is a medium to large deciduous shrub or small tree growing to 5-12 m tall, with dark brown branches and greenish twigs(Tural and Koca, 2008). The...