Myles Burnyeat has argued that in De Anima II.5 Aristotle marks out a refined kind of alteration which is to be distinguished from ordinary alteration, change of quality as defined in Physics III.1-3. Aristotle’s aim, he says, is to make it clear that perception is an alteration of this refined sort and not an ordinary alteration. Thus, it both supports his own interpretation of Aristotle’s vie...

I read with great interest the recent article by Papiamonis et al.1 One gastrointestinal complication that is seen with an increased frequency in patients with Cornelia de Lange syndrome and that is often under-reported is intestinal volvulus. Volvulus in Cornelia de Lange syndrome is most common in the cecal portion of the intestine. Non-fixation of the caecum is the most common attributable c...

It is true that mycological culture has a higher specificity, but it has lower sensitivity as compared to histopathology with periodic acid-Schiff staining (HP/ PAS).[1,2] HP/PAS is relatively quick, and a specificity of 72% cannot be overlooked.[3] In most cases, morphological aspect of the hyphae and/or spores can suggest the group to which pathogens belong.[3] In personal view of the authors...

OBJECTIVES Cornelia de Lange syndrome (CdLS) is a genetic syndrome with multisystem abnormalities. Infections are a significant cause of morbidity and mortality. The goals of our study were to identify the frequency and types of infections in CdLS and to determine if underlying immunodeficiency contributes to the clinical spectrum of this syndrome. METHODS We assessed infectious histories in ...

cornelia de lange syndrome (cdls) is a rare syndrome characterized by multiple congenital anomalies, mental retardation, characteristic facial appearance, developmental delay, skeletal malformation, hirsutism, and various cardiac and ophthalmological problems. the diagnosis of this syndrome is clinical. the patient of the present case report was the second case of cdls from iran ; only a few ca...