Corneal ectasia, a weakening of corneal integrity, occurs both due to acquired and congenital conditions such as keratoconus. It is a progressing condition that affects both visual acuity, and corneal stability. Various methods exist for correcting this impairment, however none address the inherit pathology, an increase laxity of the corneal stroma. Collagen cross-linking, a new, minimally inva...

Since the late 1990s corneal crosslinking (CXL) has been proposed as a new possibility to stop progression of keratoconus or secondary corneal ectasia, with the promising aim to prevent progressive visual loss due to the evolution of the pathology and to delay or avoid invasive surgical procedures such as corneal transplantation. The possibility of strengthening corneal tissue by means of a pho...

Ectasia After SMILE: Correct Interpretation of Biomechanical Hypothesis We read the case report by Mattila and Holopainen on bilateral ectasia after SMILE in the July 2016 issue with great interest.1 It is evident that preoperative examination with topography, tomography, and slit-lamp examination needs to be strictly followed by surgeons before small incision lenticule extraction (SMILE), LASI...

PURPOSE To assess the outcomes of intrastromal corneal ring (ISCR) implantation for the treatment of corneal ectasia. METHODS Thirty-five consecutive patients with secondary corneal ectasia treated with keraring intrastromal corneal ring segment implantation aided by intralaser femtosecond technique (K-ICRS-FS) were evaluated. Visual acuity (logMAR), refraction and astigmatism vector analysis...

Introduction. To determine the effect of corneal collagen cross-linking treatment on keratoconus and post-LASIK ectasia particularly after an abbreviated exposure to ultraviolet light exposure. Materials and methods. Fifty-one eyes of 34 patients were treated with epithelium-off UVA-riboflavin corneal collagen cross-linking for either 20 minutes or 30 minutes as part of a US.FDA clinical study....

collagen fibrils, extracellular empty spaces(likelyclefts formedfromlipid removalduringprocessing), andpersistentlyactivatedkeratocytesaresimilar to these animal findings. The extracellular lipid collections, which likelycorrespondtothecrystallinedeposits seen clinically, probably arise fromchronicmechanical irritation to keratocytes that continually strive to heal the stromal wound. The breaks...

PURPOSE To develop a computational approach to corneal biomechanical risk analysis in refractive surgery and to investigate its utility in an enigmatic case of unilateral ectasia after bilateral LASIK. METHODS Preoperative corneal elevation datasets from both eyes of a patient who developed unilateral post-LASIK ectasia were used to construct geometrically patient-specific, microstructurally ...

A thirty-nine year old man was referred to our institute due to progressive decreased visual acuity five years after bilateral Laser in situ Keratomileusis (LASIK). Topography revealed signs of post - LASIK ectasia. Patients' left eye was treated with simultaneous Topography Guided Photorefractive Keratectomy (PRK) followed by Corneal Collagen Cross Linking (CXL). Twelve months after the combin...

O ver the years, refractive surgeons have devised strategies for coping with some of the more common complications that can occur after LASIK. Nonetheless, ectasia, a condition characterized by a progressive increase in corneal curvature, remains somewhat of a mystery. Its most likely causes appear to be undetected preoperative keratoconus and excessively deep keratectomies. This article presen...

KERATOCONUS: ASYMMETRIC DISEASE Keratoconus is a non-inflammatory corneal ectasia with bilateral involvement in over 90% of patients. However, in a study of 83 patients diagnosed at presentation Burns and coworkers demonstrated there is significant asymmetry of disease both for corneal shape and visual acuity. Quantitative topographical indices reflected changes in corneal power which correlate...