recent advances in nanotechnology have rapidly developed new therapeutic and diagnostic concepts in all aspects of medicine. magnetic nanoparticles (mnps) can be simultaneously functionalized and guided by a magnetic field, thus providing promising tools for several biomedical applications. mnps contrast agents at low concentrations offer the potential to significantly improve existing methods o...

background: nowadays, magnetic nanoparticles (mnps) have received much attention because of their enormous potentials in many fields such as magnetic fluid hyperthermia (mfh). the goal of hyperthermia is to increase the temperature of malignant cells to destroy them without any lethal effect on normal tissues. to investigate the effectiveness of cancer therapy by magnetic fluid hyperthermia, fe...

Iron oxide exhibits fascinating physical properties especially in the nanometer range, not only from the standpoint of basic science, but also for a variety of engineering, particularly biomedical applications. For instance, Fe3O4 behaves as superparamagnetic as the particle size is reduced to a few nanometers in the single-domain region depending on the type of the material. The superparamagne...

Iron oxide exhibits fascinating physical properties especially in the nanometer range, not only from the standpoint of basic science, but also for a variety of engineering, particularly biomedical applications. For instance, Fe3O4 behaves as superparamagnetic as the particle size is reduced to a few nanometers in the single-domain region depending on the type of the material. The superparamagne...

Fe2O3-Al2O3 compounds with different Fe/Al compositions were synthesized by coprecipitation (CP) method and calcined at 300°-1000°C. The formation of crystalline phases (e.g., maghemite, hematite), transformation temperature, specific surface area, lattice parameter, crystallite size, magnetic properties of iron oxide were all affected by the component ratio and thermal treatment.

Hyperthermia therapy is a medical treatment based on the exposition of body tissue to slightly higher temperatures than physiological (i.e., between 41 and 46 °C) to damage and kill cancer cells or to make them more susceptible to the effects of radiation and anti-cancer drugs. Among several methods suitable for heating tumor areas, magnetic hyperthermia involves the introduction of magnetic mi...

Abstract One of the main challenges in hyperthermia treatment is how to improve heating performance nanoparticles with high specific loss power (SLP). To tackle this challenge, magnetite (MNPs) and coated polyvinyl alcohol (PVA@MNPs) were fabricated via ultrasonic-assisted coprecipitation technique. The obtained characterized by using FT-IR, TEM, TGA, XRD, ICP-OES, DLS, zeta potential, VSM UV–V...

In this paper, we simulate magnetic hyperthermia process on a mathematical phantom model representing cancer tumor and its surrounding healthy tissues. The temperature distribution throughout the phantom model is obtained by solving the bio-heat equations and the consequent cell death amount is calculated using correlations between the tissue local temperature and the cell death rate. To have a...