A glycine to valine substitution at codon 12 (G12V) in Kirsten-Ras (K-Ras) gene has been associated with reduced overall survival in colorectal cancer patients; however, the effect of other K-Ras mutations than G12V still remains unclear. Therefore, we investigated the role of different K-Ras mutations on overall survival in a homogeneous, large patient cohort with standardized therapy and unif...

bailsman is commitment to summon party .this commitment on suspect of some, cause dominate on the third-party .for this reason, some have questioned the validity of contract, other groups have attempted to justify the validity of the contract with using of joint and several liability and advocacy. in sunni jurisprudence, the first tool used and in shiie, the second tool. but the truth is that t...

This paper formulates a bilateral account of harmony that is an alternative to one proposed by Francez. It builds on for unilateral logic K\"urbis and the observation reading rules connectives bottom up gives grounds consequences formulas with opposite speech act. I formulate process call 'inversion' which allows determination assertive elimination from introduction rules, rejective conversely....

background: leptin plays a key role in the regulation of energy expenditure and is known to circulate in both free and bound forms. soluble leptin receptor (sob-r) is a unique circulating form of leptin receptor that can bind to leptin. leptin and leptin receptor have been implicated in processes leading to breast cancer initiation and progression. our study was aimed to investigate the relatio...

Background & Objective: Gliomas are the most common type of primary intracranial tumors in adults. The expression of estrogen receptors varies in different grades of glial tumors, and some studies have suggested that this expression might have a prognostic value. It seems that estrogen receptor expression negatively correlates with the histological grade of gliomas. In the pres...

We survey in this chapter the connections between Machine Learning and Control Theory. Theory provide useful concepts tools for Learning. Conversely can be used to solve large control problems. In first part of paper, we develop reinforcement learning Markov Decision Processes, which are discrete time second part, review concept supervised relation with static optimization. Deep extends learnin...

Abstract Christian nationalist ideology was among the strongest predictors of Americans voting for Trump in 2016 and remained a strong predictor intent to vote him prior 2020 election. This study uses national data examine whether nationalism could potentially convert previously-unconverted supporting or, conversely, prevent apostatizing from Trump. Among who did not 2016, increased likelihood ...

This study was undertaken to survey impacts of bottom trawling on distribution and diversity of gastropods of the Bahrakan Fishing Area (BFA), of the northwestern coasts of the Persian Gulf. Gastropod samples were collected from depths of 6m and 10m at 18 randomly selected stations in three occasions, right before the opening of shrimp trawling seasonand two weeks and 3 months after the fish...

Empirical studies have shown that the size distribution of firms can be described as a lognormal or Pareto distribution. However, these studies have focused on developed countries and little attention has been devoted to developing countries. Using the variable of number of employees as a measure of firm size, this paper investigates the shape of firm size distribution in the food & beverages i...

Strong doctor-patient relationships generate greater patient satisfaction and compliance with physician recommendations. Although prior research has explored distinct factors driving favorable patient outcomes, investigations have yet to comprehensively address the efficacy of different communication styles. Furthermore, it is critical to explore the full impact communication approaches have on...