Two algorithms are proposed for estimating the quadratically coupled frequency pairs (QC pairs) in a signal consisting of complex sinusoids in white noise, which may be nongaussian in general. Three matrices are constructed from the complex third order moments of the noisy signal, the latter two being time shifted versions of the first. The list of coupled frequencies is obtained from the rank ...

We present new light-curve measurements of Pluto and Charon taken with the Advanced Camera for Surveys High-resolution Camera on the Hubble Space Telescope. The observations were collected from 2002 June to 2003 June at 12 distinct sub-Earth longitudes over a range of solar phase angle 0. ◦36–1. ◦74—a larger range than previously measured. The new measurements of Pluto show that the light-curve...

This paper presents a planar biochip consisting of electromagnetically coupled, symmetric, square open loops for the multiparameter microwave characterization of deionized water, a phosphate-buffered saline solution, and a fructose-deionized water solution. The characterization additionally includes the probing of an ultralow glucose concentration in a very small volume of human sera and in sol...

Paclitaxel is a promising drug in the treatment of different solid tumors. It exhibits nonlinear pharmacokinetics, particularly when administered as a constant rate infusion for shorter duration (e.g., 3 h). Because of the nonlinearity, relatively small changes in dose may lead to large changes in peak plasma concentration and total drug exposure. The study was conducted to evaluate the pharmac...

Radiation propagating over cosmological distances can probe light weakly interacting pseudoscalar (or scalar) particles. The existence of a spin-0 field changes the dynamical symmetries of electrodynamics. It predicts spontaneous generation of polarization of electromagnetic waves due to mode mixing in the presence of background magnetic field. We illustrate this by calculations of propagation ...

Didanosine (ddI) is a component of highly active antiretroviral therapy drug combinations, used especially in resource-limited settings and in zidovudine-resistant patients. The population pharmacokinetics of ddI was evaluated in 48 healthy volunteers enrolled in two bioequivalence studies. These data, along with a set of co-variates, were the subject of a nonlinear mixed-effect modeling analys...

How well can the maximum size of an independent set, or the minimum size of a dominating set of a graph in which all degrees are at most d be approximated by a randomized constant time algorithm ? Motivated by results and questions of Nguyen and Onak, and of Parnas, Ron and Trevisan, we show that the best approximation ratio that can be achieved for the first question (independence number) is b...