Centrally located tumours have long been considered to be more serious, multifocal and more likely to recur. In fact, this is not the case; the only real problem is ensuring that the breast is preserved with a “normal” form following breast-conserving surgery and adjuvant radiotherapy. As with more peripheral tumours, central tumours may also benefi t from breast-conserving surgery. Several tec...

OBJECTIVE To assess the safety, cosmetic effects, and clinical efficacy of breast-conserving surgery combined with intraoperative radiation therapy for the treatment of Chinese patients with breast cancer. METHODS Breast-conserving surgery combined with intraoperative radiation therapy was performed in 64 breast cancer patients. The postoperative short-term efficacy, safety, and cosmetic effe...

Breast cancer is the most common female cancer in Western populations, affecting 12.5% of women, with 1.38 million patients per year. Breast-conserving surgery followed by postoperative radiotherapy replaced the radical and modified-radical procedures of Halsted and Patey as the standard of care for early-stage breast cancer once the overall and disease-free survival rates of breast-conserving ...

Hypothesis / aims of study Some lower urinary tract dysfunctions remain unexplained after a urodynamic testing. Functional etiology is then considered. A comprehensive care combining muscular training and behavioral and cognitive therapy (BCT) [1-2] can be proposed before a more invasive investigation. In our practice, this approach is mainly applied to patients who complain of urgency frequenc...

A liquid in the vicinity of a solid-liquid interface (SLI) may exhibit complex structures. In this study, we used molecular dynamics simulations demonstrating for the first time that the liquid adjacent to the SLI can have a two-level structure in some cases: a major structure and a minor structure. Through a time-averaging process of molecular motions, we identified the type of the liquid stru...

This Working Paper should not be reported as representing the views of the IMF. The views expressed in this Working Paper are those of the author(s) and do not necessarily represent those of the IMF or IMF policy. Working Papers describe research in progress by the author(s) and are published to elicit comments and to further debate. Although the economic growth literature has come a long way s...

BACKGROUND The optimal sequence of radiotherapy (RT) and hormone therapy using aromatase inhibitors (AI) in patients with breast cancer treated with breast-conserving surgery is unclear. Several short-term analyses have shown that there are no differences in breast cancer outcomes according to the treatment sequence. However, long-term outcomes have not been reported. PATIENTS AND METHODS We ...

3. Agarwal S, Agarwal S, Neumayer L, Agarwal JP. Therapeutic nipple-sparing mastectomy: trends based on a national cancer database. American journal of surgery. 2014;208(1):93–8. 4. McLaughlin SA. Surgical management of the breast: breast conservation therapy and mastectomy. The Surgical clinics of North America. 2013;93(2):411–28. 5. 114th United States Congress. Breast Cancer Patient Educatio...

[This corrects the article DOI: 10.1371/journal.pone.0191056.].

Behaviour Change Technique Taxonomy v1 (BCTTv1) has been used to detect active ingredients of interventions. The purpose of this study was to evaluate effectiveness of user training in improving reliable, valid and confident application of BCTTv1 to code BCTs in intervention descriptions. One hundred sixty-one trainees (109 in workshops and 52 in group tutorials) were trained to code frequent B...