An 89-year-old woman with recurrent conjunctival mucoepidermoid carcinoma developed intraocular inflammation and an elevated fundus lesion that simulated choroidal detachment in her affected right eye. Intraocular invasion of squamous cell carcinoma was suspected and the eye was enucleated. Pathologic examination of the enucleated eye showed intraocular invasion by conjunctival mucoepidermoid c...

PURPOSE/METHODS To describe one case of invasive squamous cell carcinoma of the conjunctiva in a 74-year-old woman, who two years previously had presented with a lesion which appeared to be an anterior nodular scleritis. RESULTS/CONCLUSIONS An anterior nodular scleritis, which did not respond to therapy, preceded the development of a squamous cell carcinoma of the conjunctiva adjacent to it. ...

Comment. Intraocular invasion of conjunctival squamous cell carcinoma is rare. The Bowman membrane is a thick acellular layer composed largely of collagenous tissue. Due to its structure, it often acts as an impenetrable barrier to the intraocular spread of conjunctival melanoma.Moreaggressivehistologicvariants that have a greater potential for invasion include spindle cell and mucoepidermoid c...

abstract carcinoma of the vulva has commonly been recognized as a disease of postmenopausal women, but some cases have been reported in young women during pregnancy. medical records were reviewed for a patient with vulvar carcinoma diagnosed in pregnancy. using medline and cross references, pertinent articles were sought and reviewed. a 28-year-old afghan woman in her sixth pregnancy presented ...

Four cases of conjunctival squamous carcinoma invading the cornea are presented. The surgical technique of excising the tumours from the cornea by lamellar keratectomy is described. Histology of the lesions showed well differentiated squamous carcinoma invading the superficial layers of the cornea only. Large invasive squamous cell carcinomas of the cornea result because of neglect of small par...

Proposed by Lee and Hirst, the phrase ocular surface squamous neoplasia (OSSN) includes the clinical continuum of mild, moderate, and severe dysplasia, carcinoma in situ, and invasive squamous cell carcinoma (SCC).[1] It is important to understand that dysplasia and carcinoma in situ, together constituting conjunctival intraepithelial neoplasia (CIN), are premalignant by definition, and SCC is ...

back ground: the aim of this study was to characterize the immunohistochemical expression of galectin 1, 3, and 9 in normal oral epithelium, oral squamous papilloma, and oral squamous cell carcinoma. materials and methods: immunohistochemical staining for galectins 1, 3, and 9 was evaluated in 8 samples of normal oral squamous epithelium, 15 samples of oral squamous papilloma, and 41 samples of...

the aim of this study is to determine whether there is a role of podoplanin and glutathione s-transferases t1 (gst-t1) expression in laryngeal squamous cell carcinoma. the study was completed with 33 patients and gene expression analysis was performed by qrt–pcr. the podoplanin and gst-t1 expression patterns were analyzed to determine their correlation with clinicopathologic parameters of laryn...

background: oral cancer is among the 10 most common cancers worldwide with an increasing global incidence. compromised antioxidant defense system plays a role in occurrence of cancer. this study evaluated the salivary antioxidant level of oral cancer patients compared to a control group. patients and methods: this case-control study was conducted on 22 oral squamous cell carcinoma patients pres...