Conjugated linoleic acid is a mixture of positional and geometric isomers of linoleic acid with two conjugated unsaturated double bonds at various carbon positions in the fatty acid chain. An increasing interest on CLA is attributed to its potential health benefits such as anticarcinogenic, antiatherogenic, antidiabetic and antiadipogenic effects. More than a dozen isomers of CLA are present in...

Conjugated linoleic acid (CLA) has recently attracted considerable attention as a health-promoting substance. For example, CLA has been reported to prevent carcinogenesis (Pariza and Hargraves, 1985), atherosclerosis (Nicolosi et al., 1997), and tumorigenesis (Ha et al., 1990; Ip et al., 1991), to improve hyperinsulinemia (Houseknecht et al., 1998), and to modulate immune activity (Cook et al.,...

A study was conducted to determine the effect of conjugated linoleic acid (CLA) synthesized from sunflower oil on growth, carcass characteristics and meat quality of heavy pigs. Thirty-six pigs, half barrows and half females, averaging 97 kg L.W., allotted within weight and sex to a randomized complete experimental design, were fed diets supplemented with different CLA levels: 0.5% lard (C), 0....

Conjugated linoleic acid (CLA) is known to provide certain health benefits in experimental animal models. The major CLA isomer in food is c 9,t11-CLA. A primary objective of this study was to investigate the uptake of c 9,t11-CLA and its downstream metabolites into various lipid fractions in the liver of rats fed either a high or low CLA diet (containing 0.1 or 0.8 g CLA/100 g diet, respectivel...

AIMS To observe the antiobesity activity of trans-10,cis-12-conjugated linoleic acid (CLA)-producing lactobacillus in mice. METHODS AND RESULTS Lactobacillus plantarum PL62, which can grow in the presence of linoleic acid, was selected and studied. The culture supernatant of Lact. plantarum PL62 contained trans-10,cis-12-conjugated linoleic acid (6.4 microg ml(-1)), and the crude enzyme prepa...

Conjugated linoleic acid (CLA) is presently under extensive research because of its potent anticarcinogenic effects and also because of its effects on the immune system and on lipid metabolism. The biological effects of these acids are briefly reviewed. Ruminant edible products are the richest natural sources of CLA because they are supposed to be mainly derived from rumen biohydrogenation of l...

We investigated the effects of conjugated linoleic acid (CLA) supplementation on growth, feed efficiency, carcass characteristics, meat quality, lipogenesis, and lipid metabolism in rabbits. One hundred forty-four New Zealand White rabbits, half males, half females, age 55 d, mean 1.8 kg BW, were randomly assigned to three weight- and sex-balanced feeding groups in which conventional pelleted d...

Previous research suggested that conjugated linoleic acid (CLA) feeding during the period of pubescent mammary gland development in the rat resulted in diminished mammary epithelial branching which might account for the reduction in mammary cancer risk. Terminal end buds (TEB) are the primary sites for the chemical induction of mammary carcinomas in rodents. One of the objectives of the present...

Linoleic acid is the fatty acid under which the omega-6 fatty acids, a type of ?good fat [2]?, are categorized. Conjugated linoleic acid (CLA), on the other hand, has the same molecular formula as linoleic acid but a different chemical structure. These essential nutrients aren?t produced by the human body and therefore must be ingested from plantand animal-based food products, such as vegetable...

Linoleic acid is the fatty acid under which the omega-6 fatty acids, a type of ?good fat [2]?, are categorized. Conjugated linoleic acid (CLA), on the other hand, has the same molecular formula as linoleic acid but a different chemical structure. These essential nutrients aren?t produced by the human body and therefore must be ingested from plantand animal-based food products, such as vegetable...