A non-mycoparasitic restriction enzyme-mediated DNA integration (REMI) mutant of Coniothyrium minitans (R2427) contains two tandem plasmid copies integrated towards the 3' end of an ORF. The predicted polypeptide (845 aa) exhibits high similarity with DNA-helicase proteins from other filamentous fungi and yeasts that play a role in mitochondrial DNA maintenance and repair. Disruption of the C. ...

The marine alga-derived fungus Coniothyrium cereale is a prolific producer of phenalenones. These polyketides were shown to possess antimicrobial effects and inhibitory activity towards the protease human leucocyte elastase (HLE). The current study focused on the biosynthesis of eight different structural types of phenalenones, comprising the natural products rousselianone A' (1), coniosclerodi...

Leaves from organic apple trees were dipped with different organic materials and leaves were placed on the orchard floor in autumn. Leaf area and the amount of ascospores of Venturia inaequalis were measured in spring. The objective of this research was to find alternatives for urea that simulate the decomposition of apple leaves and reduces the ascospore production. In both years urea gave an ...

The new phenalenone metabolites 1, 2, 4, and 6 were isolated from the marine-derived endophytic fungus Coniothyrium cereale, in addition to the ergostane-type sterol (3) and entatrovenetinone (5). Compounds 1 and 2 represent two unusual nitrogen-containing compounds, which are composed of a sterol portion condensed via two bonds to phenalenone derivatives. Compound 6, which contains unprecedent...

To assess the impacts of Cu and Zn on fungi, we tested the growth of 18 taxonomically different saprotrophic (basidiomycete, ascomycete and zygomycete) fungi and their production of extracellular oxidative enzymes on Cu(0, 100, 200, 400 mg kg–1) or Zn(0, 100, 200, 400 mg kg–1) containing ABTS (2,2 ́-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) agar plates. Coniothyrium sp. was the most toler...

Coniothyrium minitans (synonym, Paraphaeosphaeria minitans) is a highly specific mycoparasite of the wide host range crop pathogen Sclerotinia sclerotiorum. The capability C. to destroy sclerotia S. sclerotiorum has been well recognized and it available as widely used biocontrol product Contans WG. We present draft genome sequence Conio (IMI 134523), which previously in extensive studies that f...