Isolated Pierre Robin sequence (PRS) is characterized by underdeveloped jaw, backward displacement of the tongue and upper airway obstruction with or without cleft palate be part a known syndrome as VACTREL CHARGE, associated other malformations congenital heart disease, lung malformations, musculoskeletal system anomalies, hereditary progressive arthro-ophthalmopathy. We report neonate PRS who...

Congenital abnormalities impact 3% to 5% of allpregnancies, and they are the leading cause newborndeath. The majority caused by unknown factors, withpregnancy being sole risk factor. However, in bothaffluent developing nations, responsible forrising newborn fatalities.Aim study: purpose this study was seewhether there a link between Gestational sac diameter,crown rump length, yolk diameter feta...

background: 49, xxxxy syndrome is a rare sex chromosomal disorder, occurring in 1 per 85,000-100,000 male births. the classical phenotype is ambiguous genitalia, facial dysmorphism, mental retardation and a combination of cardiac, skeletal and other malformations. case: a two month-old boy with intrauterine growth restriction (iugr) and low birth weight, facial dysmorphism, clinodactyly in feet...

Agenesis of the lung is rare. The cases of ten patients with this malformation are recorded and illustrated. Most had congenital malformation of other organs, especially the heart, as well. All had hypoplasia of the pulmonary artery or its branches. A pantaloon-like appearance of the trachea and the main bronchi on the bronchograms is described. Exercise tolerance was impaired in all patients.

Vein of Galen malformation (VGAM) results from an aneurysmal aberration with an arteriovenous shunting of blood. Vein of Galen aneurysmal malformations are the most frequent arteriovenous malformations in infants and fetuses. The congenital malformation develops during weeks 6-11 of fetal development. Infants often die from high-output congestive heart failure.

STUDY OBJECTIVE The aim was to make an epidemiological study of major congenital heart defects and to make comparisons between groups of heart defects regarding different epidemiological variables. DESIGN The cases with congenital heart defects were identified from two Swedish registries: the Registry of Congenital Malformations and the Child Cardiology Registry. A classification with nine gr...

Abstract Pulmonary agenesis is a rare malformation associated with congenital heart disease and may lead to life-threatening condition death without pre-planned surgical medical support. We report an unusual case of unilateral pulmonary in combination total anomalous venous connection, complete vascular ring, retroaortic, retroesophageal innominate vein, secondary atrial septal defect, which wa...

background: the goal of the present study was to report the results of two parallel works in which the incidence of fetal deaths and also congenital malformations among the progenies of the iranian chemical victims were studied. methods: the subjects were progenies of a randomly selected population from survivors of chemical attacks during iran-iraq conflict. totally 807 male cases ranged 18-85...

retinoic acid (ra) plays a key role in pattern formation along the major body axis and limbformation during vertebrate development. exposure to excessive retinoic acid (in uterus) generatescongenital malformations in limbs, craniofacial, cns, urogenital, heart, and axial skeletons. in thesestudies, seven groups of nmri pregnant mice were administered a single gavage dose of 100 mg /kgbody weigh...

Certain conditions found in human congenital heart disease are probably genetic in origin (Cockayne, 1938; Polani and Campbell, 1955), but sometimes they may be correlated with an environmental factor, namely the infection of the mother with rubella during early pregnancy. Thus there appears to be no single cause of congenital heart abnormality; sometimes genetic causes and sometimes environmen...