The worldwide prevalence of extended-spectrum-beta-lactamase-producing ESBL-producing Enterobacteriaceae (ESBL-E) is increasing, making the need for optimized detection techniques more urgent. In this study we investigated the performance of two ESBL-E screening and two ESBL-E confirmation techniques. In accordance with the Dutch national guidelines (www.wip.nl), a collection of 642 highly resi...

While the incidence of Human African Trypanosomiasis (HAT) is decreasing, the control approach is shifting from active population screening by mobile teams to passive case detection in primary care centers. We conducted a systematic review of the literature between 1970 and 2011 to assess which diagnostic tools are most suitable for use in first-line health facilities in endemic countries. Our ...

background and purpose: inserting a nasogastric tube, though a common clinical procedure with widespread use for critically ill patients, can produce unexpected complications so that tube misplacement into the lungs is a potential complication with serious consequences. the reliability of common bedside methods to differentiate between pulmonary and gastric placement has not been acceptable. th...

BACKGROUND India is witnessing a rising burden of type 2 diabetes mellitus. India's National Programme for Prevention and Control of Diabetes, Cancer, Cardiovascular diseases and Stroke recommends population-based screening and referral to primary health centre for diagnosis confirmation and treatment initiation. However, little is known about uptake of confirmatory tests among screen positives...

A rapid diagnosis is considered important in HIV care. In 138,911 testing episodes with the Abbott Architect HIV Ag/Ab Combo assay (3,705 reactive samples), a signal-to-cutoff ratio of >151.17 had a positive predictive value of 100% and a sensitivity of 67.4% for the detection of subsequently confirmed HIV infection. We suggest that results higher than this signal-to-cutoff ratio threshold may ...

The availability of active safety systems, such as Lane Departure Warning (LDW), has recently been added as a rating factor in the U.S. New Car Assessment Program (NCAP). The objective of this study is to determine the relevance of the NCAP LDW confirmation test to real-world road departure crashes. This study is based on data collected as part of supplemental crash reconstructions performed on...