Configuration change management provides a way for a manufacturer to become more competitive. Because of the short life and the large variety involved in commercial products, they must be configured accordingly. It is a task for the configuration change management. This paper presents an integrated model for modeling the change behavior of product parts, and for evaluating alternative suppliers...

Changes in the configuration of proteins were studied by the modifications of the ultraviolet absorption of their alkaline solutions. These were expressed in terms of the ratio O.D.(pH12)/O.D.(pH7), termed side-group ionization ratio (SGIR). This ratio showed two peaks; one at 300 to 305 mmicro is known to correspond to the phenolic hydroxyl of tyrosine and another at 245 mmicro seems to be cau...

System configuration tools automate the configuration and management of IT infrastructures. However these tools fail to provide decent authorisation on configuration input. In this paper we apply fine-grained authorisation of individual changes on a complex input language of an existing tool. We developed a prototype that extracts meaningful changes from the language used in the Puppet tool. Th...

Spatial regulation of exocytosis relies on the exocyst, a hetero-octameric protein complex that tethers vesicles to fusion sites at the plasma membrane. Nevertheless, our understanding of mechanisms regulating exocyst assembly/disassembly, localization, and function are incomplete. Here, we have exploited a panel of anti-Sec6 monoclonal antibodies (mAbs) to probe possible configurational change...

Typical large infrastructures are currently configured from the information in a central configuration repository. As infrastructures get larger and more complex, some degree of autonomous reconfiguration is essential, so that certain configuration changes can be made without the overhead of feeding the changes back via the central repository. However, it must be possible to dictate a central p...

Cognitive abilities rise steeply from infancy to young adulthood and then are either maintained or decline to old age, depending on the specific ability. This pattern suggests corresponding continuities of mechanism and process, but it is striking that the fields of cognitive development and cognitive aging make little contact with each other's methods and theories. In this review we examine re...