for large and complex reacting systems, computational efficiency becomes a critical issue in process simulation, optimization and model-based control. mechanism simplification is often a necessity to improve computational speed. we present a novel approach to simplification of reaction networks that formulates the model reduction problem as an optimization problem and solves it using genetic al...

purpose: to develop a computational model for predicting the fluid production and flow, and intraocular pressure (iop) following glaucoma surgery. methods: to help elucidate the interplay of physical factors controlling the distribution and absorption of aqueous humor in sub-conjunctival tissue, and tissue remodeling, a computational model is developed to predict the fluid production in the eye...

Exporting to cultural heritage methods and tools used in industrial areas, where the profits can justify high modeling costs, may only be a starting point for cultural heritage modeling, but not a sustainable solution in sight of the economics of this application. A way to lower the costs is to automate the modeling procedure. This work presents a robust procedure for the automatic alignment of...

Evolutionary thinking can be applied to both cultural microevolution and macroevolution. However, much of the current literature focuses on cultural microevolution. In this article, we argue that the growing availability of large cross-cultural datasets facilitates the use of computational methods derived from evolutionary biology to answer broad-scale questions about the major transitions in h...