PTP1B bound to mature N-cadherin promotes the association of beta-catenin into the complex, the stable expression of the complex at cell surface, and cadherin-mediated adhesion. Here we show that PTP1B is also required for N-cadherin precursor trafficking through early stages of the secretory pathway. This function does not require association of PTP1B with the precursor. In PTP1B null cells, t...

The thylakoid twin arginine protein translocation (Tat) system is thought to have a multivalent receptor complex with each cpTatC-Hcf106 pair constituting a signal peptide-binding unit. Conceptual models suggest that translocation of individual precursor proteins occurs upon assembly of a Tha4 oligomer with a precursor-occupied cpTatC-Hcf106. However, results reported here reveal that multiple ...

In this study, the new benzimidazolium salt (1) containing ether functionalized alkyl group as NHC ligand precursor was synthesized. Ag-NHC complex (2) synthesized by interaction with Ag2O of precursor. The Au-NHC [AuCl(PPh3)] complex. structures prepared all compounds were characterized different spectroscopic methods. 
 Bu çalışmada, öncüsü olarak eter fonksiyonlu alkil grubu içeren yeni...

We are investigating the molecular mechanisms involved in the localization of lysosomal enzymes in Dictyostelium discoideum, an organism that lacks any detectable mannose-6-phosphate receptors. The lysosomal enzymes alpha-mannosidase and beta-glucosidase are both initially synthesized as precursor polypeptides that are proteolytically processed to mature forms and deposited in lysosomes. Time c...

in this paper, we report on the synthesis of cu nanoparticles through a single-precursor route by controlling the growth temperature. selective adsorption of oleylamine on various crystal planes may play an important role in the growth process. the understanding of this self-assembling process will help us develop reliable and reproducible methods to synthesis other three dimensional nanostruct...

Members of the mitochondrial carrier family such as the ADP/ATP carrier (AAC) are composed of three structurally related modules. Here we show that each of the modules contains a mitochondrial import signal recognized by Tim10 and Tim12 in the intermembrane space. The first and the second module are translocated across the outer membrane independently of the membrane potential, DeltaDeltapsipsi...

in this paper, plate-like nio nanoparticles were prepared by one-pot solid-state thermal decomposition of nickel (ii) schiff base complex as new precursor. first, the nickel (ii) schiff base precursor was prepared by solid-state grinding using nickel (ii) nitrate hexahydrate, ni(no3)2∙6h2o, and the schiff base ligand n,n′-bis-(salicylidene) benzene-1,4-diamine) for 30 min without using any solv...