Some issues are considered which arise when template matching is used to identify cells in differential interference contrast (DIC) microscope images. An automatic method of counting and sizing the cells in such images is proposed and two examples given. Template matching is complex due to the nature of DIC images, namely the way in which light is captured across the image. Further complication...

Workplace deviance is indeed an issue for any organization. Many researchers have endeavored to explore different predictors to control this problem. However, managerial coaching can be seen as a leading managerial practice to address this issue within the organizations. Using the LMX theory, a model was developed to explore the direct relationship between managerial coaching and workplace devi...

Eighty-one 13- to 14-year-old boys at risk for delinquency (target boys) engaged in brief dyadic conversations with their peer friends. The target boys' verbal behavior was coded into two mutually exclusive content categories, rule-break talk and normative talk. Positive social responses from peer boys for each category of talk were also recorded, and were presumed to reinforce the target boys'...

We consider the problem of comparing complex hierarchical models in which the number of parameters is not clearly defined. Using an information theoretic argument we derive a measure pD for the effective number of parameters in a model as the difference between the posterior mean of the deviance and the deviance at the posterior means of the parameters of interest. In general pD approximately c...

BACKGROUND We have previously shown highly elevated antisocial symptoms and measures of social deviance proneness and antisocial disposition in long-term abstinent alcohol dependence versus non-substance-abusing controls (NSAC). Current antisocial symptoms were reduced to subdiagnostic levels in long-term abstinence; however, the number of current symptoms was not measured beyond its being subd...

Concentration of a nonfluorescent solution was determined in a 100-nm scale channel using a differential interference contrast thermal lens microscope (DIC-TLM). The DIC-TLM detects a refractive index change induced by sample heating as phase contrast. Concentration measurement was first performed in a nanochannel which is 21 m wide and 500 nm deep. The limit of detection (LOD) was 2.4 M and th...

Abstract. We develop a novel generative model for arbitrary 2D shapes, based on multiscale deformation. We demonstrate how our model can be used to segment objects within an image by fitting a shape-sensitive contour to each object’s boundary. We demonstrate our model by performing segmentation on di↵erential interference contrast microscopy (DIC) images of yeast, where many cells possess aberr...

In this paper, we report a hidden Markov model based multiclass classification of cervical cancer tissues. This model has been validated directly over time series generated by the medium refractive index fluctuations extracted from differential interference contrast images of healthy and different stages of cancer tissues. The method shows promising results for multiclass classification with hi...

We developed a nanofluidics-based enzyme-linked immunosorbent assay (ELISA) device and realized quantification of countable number of molecules by combining enzymatic amplification reaction and ultrasensitive detection with a differential interference contrast thermal lens microscope (DIC-TLM). Our method will contribute to single cell analysis field, in particular for ultrasensitive protein co...