Irrigation has been performed in conjunction with endodontic therapy for many years. One of the primary reasons for irrigating the root canal system is to ensure cleanliness of the canals prior to obturation. This cleanliness involves both elimination of microorganisms and removal of organic matter. Sodium hypochlorite [NaOCl] is the most commonly used solution in root canal treatments, despite...

Amongst the bacterial species which most often cause endodontic failures, Enterococcus faecalis is the most important. This study compared the effectiveness of sodium hypochlorite and two new generation antibiotic-based endodontic irrigants, Tetraclean and MTAD. By means of an in vitro agar dilution assay, we show that both Tetraclean and MTAD are 100% effective against 54 clinical isolates at ...

Introduction: Historically, countless compounds in aqueous solution have been suggested as root canal irrigants. MTAD shows promise as an endodontic irrigant but there are very few studies comparing its antimicrobial effectiveness with NaOCl and Chlorhexidine. Objectives: To compare the antibacterial efficiency of MTAD, 2.5% Sodium Hypochlorite and 2% Chlorhexidine root canal irrigants against ...

Context Local administration of antimicrobial agents offer a "site-specific" approach to the periodontal therapy and it has several benefits. Aim The present study was aimed to assess the clinical and microbial changes by subgingival irrigation using different subgingival irrigants in periodontitis patients and also to assess the mechanical effect of different local irrigation devices; if any...

The aim of this study was to compare the efficacy of a new generation endodontic irrigant, Tetraclean, to the widely used sodium hypochlorite. Tetraclean combines a powerful detergent effect with a strong antimicrobial efficacy, whereas sodium hypochlorite has several drawbacks and is sometimes ineffective in preventing microbial-mediated endodontic failure. The bactericidal activity of both ir...

The key factor in the production of pulp and periapical inflammation is represented by the presence of bacteria in the root canal system and the outcoming toxins. Bacterial biofilm is identifiable in the various areas of the endodontic space, but due to the complexity of the internal anatomy of the root canal, bacteria removing is yet difficult to obtain, a particularly important step for treat...

INTRODUCTION One of the main goals of endodontic treatment is to decrease the harboring bacteria within the root canal system and dentinal tubules. This experimental study attempted to investigate the antibacterial efficacy of three root canal irrigants in the presence and absence of smear layer (SL). METHODS AND MATERIALS A total of 210 sound extracted human single-rooted teeth were prepared...

Using ultrasonic devices in endodontics can enhance the antibacterial and tissue dissolving ability of different root canal irrigants such as sodium hypochlorite (NaOCl) which is the most common irrigant with excellent antibacterial and tissue dissolving abilities. However, due to its high surface tension, its penetration into the irregularities of the root canal system is a challenge. The purp...