Calcium signalling is a highly versatile cellular communication system that modulates basic functions such as cell contractility, essential steps of animal development such as fertilization and higher-order processes such as memory. We probed the function of calcium signalling in Drosophila wing imaginal discs through a combination of ex vivo and in vivo imaging and genetic analysis. Here we di...

Production of extended-spectrum β-lactamases (ESBLs) producing E. coli in animals and different methods of identifications from Ado Ekiti, Ekiti State, Nigeria, were investigated. Three hundred and fifty fecal samples, collected from apparently healthy cattle and pigs, were cultured and identified following standard procedures. ESBL phenotypic detection was carried out using combination disc te...

Self-gravitating protostellar discs are unstable to fragmentation if the gas can cool on a time scale that is short compared to the orbital period. We use a combination of hydrodynamic simulations and N-body orbit integrations to study the long term evolution of a fragmenting disc with an initial mass ratio to the star of M disc /M * = 0.1. For a disc which is initially unstable across a range ...

Automated image processing has the potential to assist in the early detection of diabetes, by detecting changes in blood vessel patterns in the retina. This paper describes progress towards the development of an integrated automated analyser of the retinal blood vessels in the vicinity of the optic disc using digital colour retinal images. First the optic disc was detected using a combination o...

INTRODUCTION The current modalities of treating symptomatic degenerative disc disease are either conservative non-surgical or surgical modalities. Non-surgical modalities include improving body posture and back muscle strengthening through physical therapy. Surgical treatment includes removal of the disc material and intervertebral fusion, or artificial disc replacement, which is still in exper...

Fifty-eight temporomandibular joints (TMJs) from 40 patients with TMJ-related symptoms were examined by means of magnetic resonance scans with modified gradient echo sequences and a special double coil. This technique yielded a good spatial resolution of the intra-articular soft tissues, especially the articular disc and the bone structure of the TMJ. In combination with an incremental jaw open...

OBJECTIVES The aim of this study was to investigate bone changes in the condyle, articular eminence and glenoid fossa in relation to the position of the articular disc. METHODS 148 temporomandibular joints (TMJs) of 74 symptomatic patients who underwent MRI were evaluated. The position of the disc was classified as either normal (N), disc displacement with reduction (DDwR), disc displacement ...

BACKGROUND Patients with cervical radicular syndrome due to disc herniation refractory to conservative treatment are offered surgical treatment. Anterior cervical discectomy is the standard procedure, often in combination with interbody fusion. Accelerated adjacent disc degeneration is a known entity on the long term. Recently, cervical disc prostheses are developed to maintain motion and possi...