the present study was performed to investigate the effects of long-term intraperitoneal (ip) injection of vitamin b12 and diclofenac in separate and combined treatments on cold and mechanical allodynia in a neuropathic pain model in rats. neuropathic pain was induced by crush injury in right tibial nerve. acetone spray and von frey tests were used to obtain cold and mechanical allodynia respons...

temperature is an importan environmental factor that inevitably determines the extent and geographical range of plants. in this study, the chilling induced responses of 11 desi chickpea genotypes were surveyed under growth chamber conditions to screen for chilling tolerance. electrolyte leakage (el) and lipid peroxidization (malondialdehide (mda)) methods were employed for the purpose. data ana...

Salicylic acid (SA) plays an important role in the regulation of plant ripening and responses to abiotic stresses. In this study, the protective effect of SA on cold stress-caused oxidative damage in grape (Vitis vinifera L.) bunches was investigated during cold storage.  Grape bunches treated with 2 mM SA and  stored at 0°C with 85-90% RH for 30 days. Samples were selected from each treatment ...

conclusions this study showed the importance of considering syndrome differentiation and temperaments in interpreting the effect of p. granatum peels extract on ulcerative colitis. results therapeutic response was significantly higher in patients with hot temperament compared to patients with cold temperament in the p. granatum group (1.916 ± 0.492 versus -0.500 ± 0.500, p = 0.029). methods sev...

Insects experience repeated cold exposure (RCE) on multiple time scales in natural environments, yet the majority of studies of the effects of cold on insects involve only a single exposure. Three broad groups of experimental designs have been employed to examine the effects of RCE on insect physiology and fitness, defined by the control treatments: 'RCE vs cold', which compares RCE with consta...

Camellia is a well-known ornamental flower native to Southeast of Asia, including regions such as Japan, Korea and South China. However, most species in the genus Camellia are cold sensitive. To elucidate the cold stress responses in camellia plants, we carried out deep transcriptome sequencing of 'Jiangxue', a cold-tolerant cultivar of Camellia japonica, and approximately 1,006 million clean r...

Mammalian somatosenory neurons respond to thermal stimuli and allow animals to reliably discriminate hot from cold and to select their preferred environments. Previously, we generated mice that are completely insensitive to temperatures from noxious cold to painful heat (-5 to 55°C) by ablating several different classes of nociceptor early in development. In the present study, we have adopted a...

Multiple stressors, both abiotic and biotic, often are experienced simultaneously by organisms in nature. Responses to these stressors may share signaling pathways ("cross-talk") or protective mechanisms ("cross-tolerance"). Temperate and polar insects that must survive the winter experience low temperatures accompanied by additional abiotic stressors, such as low availability of water. Cold an...

17(2): 3’7-322. I g62.-Caucasian subjects from a temperate climate immersed their right index fingers in a stirred icewater bath for 20 min four times daily for I month. During subsequent test immersion, fingers exposed in this way showed an earlier initiation and a more rapid rate of spontaneous rewarming and a higher and more labile final temperature level than did either the same finger befo...