background: low back pain (lbp) is one of the most common problems among the workers of different industries. the role of occupational factors in causing the lbp has been indicated previously. lbp has great socio-economic costs and most of its costs are related to the chronic lbp. the aim of this study was to identify the occupational risk factors that are related to the progression of the lbp ...

Aim: As to the assessment of occlusal status pertaining to primary canines and molars, the latter is less within reach as it is difficult to guide jaws towards a centric occlusion while maintaining a vintage point in both direct and indirect observation.  This study was originally intended to assess primary canine occlusion as a practical indicator in the evaluation of primary molar occlusion, ...

hepatitis b virus (hbv) infection is the most common cause of end stage liver disease in iran and in golestan province. large-scale population-based prospective cohort studies with long term follow-up are the method of choice to accurately understand the natural course of hbv infection. to date, several studies of hbv epidemiology, natural history, progression to cirrhosis and association with ...

Multiple studies have demonstrated decreased recidivism and increased treatment engagement for individuals with serious mental illness involved in Mental Health Courts (MHC). However, the limited availability of social and fiscal resources requires an analysis of the relationship between a program's effectiveness and its costs. Outcome costs associated with a sample of 105 participants discharg...

Recent work has demonstrated that nonstimulatory endogenous peptides can enhance T cell recognition of antigen, but MHCI- and MHCII-restricted systems have generated very different results. MHCII-restricted TCRs need to interact with the nonstimulatory peptide-MHC (pMHC), showing peptide specificity for activation enhancers or coagonists. In contrast, the MHCI-restricted cells studied to date s...

BACKGROUND Few studies have considered source-specific micronutrient intake in relation to mortality under the consideration that dietary and supplemental intake could exhibit different effects. OBJECTIVE To evaluate the association between intake of vitamin C, E, folate, beta-carotene from diet and supplements, and overall mortality. Furthermore, to examine effect modification by smoking, al...

The genetic and epigenetic influences that are responsible for the establishment and maintenance of the unique phenotype of the extraocular muscles (EOMs) are poorly understood. A role for visual cues in shaping EOM maturation was assessed in rats by using two visual deprivation paradigms, dark rearing and monocular deprivation. Isoforms of the contractile protein myosin heavy chain (MHC) were ...

Mesophotic hard corals (MHC) are increasingly threatened by a growing number of anthropogenic stressors, including impacts from fishing, land-based sources of pollution, and ocean acidification. However, little is known about their geographic distributions (particularly around the Pacific islands) because it is logistically challenging and expensive to gather data in the 30 to 150 meter depth r...

Vaccines are the greatest single instrument of prophylaxis against infectious diseases, with immeasurable benefits to human wellbeing. The accurate and reliable prediction of peptide-MHC binding is fundamental to the robust identification of T-cell epitopes and thus the successful design of peptide- and protein-based vaccines. The prediction of MHC class II peptide binding has hitherto proved r...