Introduction Electroconvulsive therapy (ECT) is one of the most controversial treatments in medicine, mainly because its still unknown mechanism action and uncertainty about cognitive side effects. ECT used when antidepressant medications do not result an adequate response severe depression, may also be indicated for other disorders. During acute phase after electroconvulsive there are better o...

Cognitive impairments and depression have considerable impacts on rehabilitation, quality of life and mortality after stroke. The understanding of cognitive and mood impairments in old and, in particular, very old stroke patients is not sufficient. The knowledge of the frequency of neglect, its relation to other cognitive impairments is meager, in the elderly and late after stroke despite its k...

OBJECTIVES To assess the relationship of disability (activities of daily living (ADL) and instrumental ADL (IADL)), self-rated health (SRH), and 6-year mortality with co-existing impairments in vision (self-rated), hearing (self-rated) and/or cognition (Short Portable Mental Status Questionnaire) in older adults. METHODS The study sample was comprised of 3871 participants from the North Carol...

BACKGROUND Cognitive impairments have been extensively reported for patients suffering from schizophrenia but a lot of questions persist about these troubles. Several domains of cognitive functions are impaired which result in daily life difficulties. Many arguments tend to show that children suffering from psychotic spectrum disorders present cognitive impairments also but things are not clear...

Recently neuro-inflammation and cognitive impairment has attracted attention. It has been suggested that obesity lead to cognitive impairments induced by neuro-inflammatory markers like nuclear factor kappa B (NF-kB) and reduced neurotrophin factors like brain-derived neurotrophic factor (BDNF) in the hippocampus. Also, increased blood brain barrier (BBB) permeability. Because of the neuro-prot...