A rare case of 40 years old female, came with complaints pain and blurring vision in the left eye for past week. The patient had a diminution since birth her eye. On examination was found to be 6/60 not improving pinhole, also defective color 20/25. right-eye normal. showed significant corneal edema, moderate anterior chamber depth, iris features Corectopia, Pseudopolycoria, atrophy. Pressures ...

Cogan’s syndrome is a rare, multisystem disease which occurs predominantly in children and young adults. It was originally described as the combination of interstitial keratitis and audiovestibular disturbance, but other forms of ocular disease, as well as systemic vasculitis, have since been recognised as part of the syndrome. Diagnosis can be diYcult if the various manifestations occur separa...

Cogan’s Syndrome (CS) is a disease affecting young adults and consists of episodes of acute interstitial keratitis with vestibuloauditory dysfunction. This syndrome was originally described in 1945 by Cogan as a disorder of the eyes and ears, characterized by nonsyphilitic interstitial keratitis with deafness. Sporadic reports showing the development of vasculitis in patients with eye and ear d...

The presence of a layer of abnormal material in Descemet's membrane in eight keratoplasty specimens served as a marker to determine whether Chandler's syndrome, Essential Iris Atrophy, and the Cogan-Reese syndrome are congenital or acquired conditions. In all eight cases of the ICE syndrome, a pattern of membrane deposition was observed, which typifies acquired disorders: a completely normal pr...