Tinnitus, the perception of a monotonous sound not actually present in the environment, affects nearly 20% of the population of the United States. Although there has been great progress in tinnitus research over the past 25 years, the neurochemical basis of tinnitus is still poorly understood. We review current research about the effects of various types of cochlear damage on the neurotransmitt...

cochlear implantation is a method used for the treatment of patients with profound hearing loss. this procedure may the accompanied by some major or minor complications. we evaluated the surgical complications of cochlear implantation in fars province (south of iran). a total of 150 patients with cochlear implantation were enrolled in the present study. most of the patients were pre-lingual chi...

Cochlear implant devices are designed to provide sound sensation and improved speech understanding to people who are profoundly hearing impaired. Best speech recognition could be achieved by using multi-channel, multi-electrode cochlear implant devices. In a multichannel cochlear prosthesis, channel interaction and tissue damage are important issues to be solved. Speech processing and modidatio...

Excessive exposure to noise damages the principal cochlear structures leading to hearing impairment. Inflammatory and immune responses are central mechanisms in cochlear defensive response to noise but, if unregulated, they contribute to inner ear damage and hearing loss. Transforming growth factor β (TGF-β) is a key regulator of both responses and high levels of this factor have been associate...

In the fifty years since Békésy was awarded the Nobel Prize, cochlear physiology has blossomed. Many topics that are now current are things Békésy could not have imagined. In this review we start by describing progress in understanding the origin of cochlear gross potentials, particularly the cochlear microphonic, an area in which Békésy had extensive experience. We then review progress in area...

Prolonged Exposure to Industrial Noise: Cochlear Pathology does not Correlate with the Degree of Permanent Threshold Shift, but is Related ́ ́ to Duration of Exposure: Mariola SLIWINSKA-KOWALSKA, et al. Department of Physical Hazards, The Nofer Institute of Occupational Medicine—It has been shown that the damaging effects of noise on the mammalian inner ear strongly depend upon parameters of exp...

Cochlear implantation is a method used for the treatment of patients with profound hearing loss. This procedure may the accompanied by some major or minor complications. We evaluated the surgical complications of cochlear implantation in Fars province (south of Iran). A total of 150 patients with cochlear implantation were enrolled in the present study. Most of the patients were pre-lingual chi...

Acoustic overstimulation and ototoxic drugs can cause permanent hearing loss as a result of the damage and death of cochlear hair cells. Relatively little is known about the signaling pathways triggered by such trauma, although a significant role has been described for the c-Jun N-terminal kinase [one of the mitogen-activated protein kinases (MAPKs)] pathway. We investigated the role of another...