Intra-cochlear fibrous tissue formation around the electrode following cochlear implantation affects impedance as well explantation during reimplantation surgeries. Applying corticosteroids in is one way of minimizing intra-cochlear electrode. It were J. Kiefer, C. von Ilberg, and W. Gstöttner who proposed first idea on drug delivery application to MED-EL year 2000. During twenty years translat...

Automatic methods to segment the vestibular schwannoma (VS) tumors and cochlea from magnetic resonance imaging (MRI) are critical VS treatment planning. Although supervised have achieved satisfactory performance in segmentation, they require full annotations by experts, which is laborious time-consuming. In this work, we aim tackle segmentation problem an unsupervised domain adaptation setting....

Decay starts right after death. It is well known that decay begins in the lower left abdomen and spreads from there through body. Aim of our study was to observe enclosed air death cochlea.

Spiking cochlea models describe the analog processing and spike generation process within the biological cochlea. Reconstructing the audio input from the artificial cochlea spikes is therefore useful for understanding the fidelity of the information preserved in the spikes. The reconstruction process is challenging particularly for spikes from the mixed signal (analog/digital) integrated circui...

We have examined one of the metabolic consequences of unilateral cochlea (basilar papilla) removal in the chick brain stem auditory system. We assessed changes in succinate dehydrogenase (SDH), a mitochondrial enzyme involved in energy metabolism, in neurons of second-order n. magnocellularis (NM) and third-order n. laminaris (NL). Chickens undergoing surgery at 10 days of age were perfused 4 h...

Synaptophysin and synaptobrevin 2 associate closely with packaging and storage of synaptic vesicles and transmitter release, and both play important roles in the development of rat cochlea. We examined the differential expression of synaptophysin and synaptobrevin 2 in the developing Sprague-Dawley rat cochlea, and investigated the relationship between their expression and auditory development....

BACKGROUND It has been reported that one of the main mechanisms that induces the activation of the cochlea through infrared laser light is the photothermal effect. The temperature in the spiral ganglion cells increases as a result of photon absorption. However, heat conduction can induce an increase in the temperature within the cochlea and change the spatial selectivity of activation. METHOD...

Cells of the inner ear face constant metabolic and structural stress. Exposure to intense sound or certain drugs destroys cochlea hair cells, which in mammals do not regenerate. Thus, an endogenous stress response system may exist within the cochlea to protect it from everyday stressors. We recently described the existence of corticotropin-releasing factor (CRF) in the mouse cochlea. The CRF re...

OBJECTIVES/HYPOTHESIS To assess whether transcanal endoscopic access to the basal turn of the cochlea for cochlear implantation is appropriate. STUDY DESIGN Case series study. METHODS We reviewed 100 consecutive computed tomographic studies of the sinuses and temporal bone in our institution. We excluded studies that demonstrated evidence of congenital anomalies, chronic ear disease, or ina...

BACKGROUND There have been reports that maxillofacial firearm wounds could induce hearing loss. The effects on the ultrastructure of the cochlea and cochlear nerves after oral and maxillofacial firearm wounds are still unclear. This experiment investigates the ultrastructural changes of the cochlea and cochlear nerve after oral and maxillofacial firearm wounds. METHODS Twenty dogs were wounde...