Background: The aim of this study was to review and characterize the pattern of CNS lesions in patients suffering from AIDS and to correlate these patterns with clinical disorders. Method: The MR scan, medical records and laboratory findings of 58 AIDS patients were reviewed retrospectively during April 1994 to November 1997 at the Olive view/UCLA and Shiraz Medical Centers, and the patterns o...

Introduction Intracranial infections involving the bones of the skull or spine (osteomyelitis), the extradural compartments, the pachymeninges (dura), subdural space, leptomeninges and subarachnoid space are mainly caused by bacteria and occasionally by fungi and viruses (leptomeningitis). The organisms that infect the CNS itself (the brain and the spinal cord) are mainly viruses and bacteria, ...

This is a brief report of the 19th Annual Meeting of the American Society of Gene and Cell Therapy that took place from May 4th through May 7th, 2016 in Washington, DC, USA. While the meeting provided many symposiums, lectures, and scientific sessions this report mainly focuses on one of the sessions on the "Gene Therapy for central nervous system (CNS) Diseases" and specifically on the "Gene T...

Central nervous system (CNS) is an immune privileged site, nevertheless inflammation associates with many CNS diseases. Peroxisome proliferator-activated receptors (PPARs) are a family of nuclear hormone receptors that regulate immune and inflammatory responses. Specific ligands for PPARalpha, gamma, and delta isoforms have proven effective in the animal models of multiple sclerosis (MS), Alzhe...

A Central nervous system (CNS) hemorrhage is bleeding in or around the brain and spinal cord. Reasons of CNS hemorrhage include high blood pressure, cancers, drug abuse, abnormally weak blood vessels that leakage, and trauma. Regression of CNS bleeding was confirmed to be relatively repetitive in patients with severe FV, FX, FVII and FXIII deficiencies. Generally in CNS hemorrhage, radiological...

Treatments for disease in the central nervous system (CNS) are limited because of difficulties agent penetration through blood-brain barrier, achieving optimal dosing, and mitigating off-target effects. The prospect precision medicine CNS treatment suggests an opportunity therapeutic nanotechnology, which offers tunability adaptability to address specific diseases as well targetability when com...

Chlamydia infections are common that transmitted through sexual C. pneumonia is a pathogen causes different acute and chronic infections. Due to the increase in biological knowledge use of more sensitive specific techniques detection recent years, it thought has role various cardiovascular central nervous system (CNS) diseases. There increasing evidence may have neurologic diseases, especially ...

Thrombin is a multifunctional enzyme which has key roles in coagulation cascade and inflammatory events. The pro-inflammatory functions of thrombin occur by different mechanisms including increasing mast cell degranulation, up-regulating the expression of cell adhesion molecules (CAMs) and promoting the secretion of inflammatory chemokines and cytokines. Dysregulated signaling functions of thro...

The paper presents one of the options for automating evaluation procedures magnetic resonance imaging (MRI) brain in patients suffering from most severe diseases central nervous system (CNS), multiple sclerosis.

background: the aim of this study was to review and characterize the pattern of cns lesions in patients suffering from aids and to correlate these patterns with clinical disorders. method: the mr scan, medical records and laboratory findings of 58 aids patients were reviewed retrospectively during april 1994 to november 1997 at the olive view/ucla and shiraz medical centers, and the patterns of...