objective(s):previous studies demonstrate that changes in pre-mrna splicing play a significant role in human disease development. furthermore, many cancer-associated genes are regulated by alternative splicing. there are mounting evidences that splice variants which express predominantly in tumors, have clear diagnostic value and may provide potential drug targets. located on the x chromosome, ...

Graded fly ash particles have many useful industrial applications due to its fineness and spherical shape. However, grading of fly ash in an industrial scale is a challenging task. The possibility of using hydrocyclones for this purpose has been demonstrated here based on carefully conducted laboratory experiments. The primary objective of this research is to study the effectiveness of a classi...

background: primary gastric lymphoma (pgl) is an uncommon malignancy with various histological subtypes and treatment outcomes. the aim of this study was to investigate the potential prognostic factors and clinicopathological characteristics of iranian patients with pgl. methods: the clinicopathological characteristics of 60 patients with pgl were retrospectively reviewed from 2001 to 2012. the...

Objective(s):Previous studies demonstrate that changes in pre-mRNA splicing play a significant role in human disease development. Furthermore, many cancer-associated genes are regulated by alternative splicing. There are mounting evidences that splice variants which express predominantly in tumors, have clear diagnostic value and may provide potential drug targets. Located on the X chromosome, ...

In this study, nonlinear vibration of axially moving strings in thermal environment is investigated. The vibration haracteristics of the system such as natural frequencies, time domain response and stability states are studied at different temperatures. The velocity of the axial movement is assumed to be constant with minor harmonic variations. It is presumed that the system and the environment...

background: the lysosomal protease cathepsin d (cd) has been associated with tumor progression in malignant tumors including oral squamous cell carcinoma (oscc). the purpose of this study was to find out any association between the cd and lymph node metastasis and to study the correlation of cd with various clinicopathological parameters to aid in assessment of its role as a prognostic indicato...

A 53-year-old man was admitted to Keio University Hospital because of serious dyspnea and edema of the lower extremities. Eighteen months previously, the patient had complained of chest discomfort, and was then admitted for the first time to our hospital for evaluation of chest pain. Electrocardiography showed poor R wave progression in leads Vl through V4, and diffuse nonspecific STsegment and...

The article presents the results of morphological and anatomical analysis Cystoseira sensu lato taxa in flora Ukraine, taking into account modern views on nomenclature genus. Earlier, based molecular phylogenetic analysis, it was shown that along Ukrainian shores polyphyletic genus s. l. is represented by three (Ericaria crinita f. bosphorica (Sauvageau) S.S.Sadogurska, J.Neiva et A.Israel., Go...

It is a challenging task to diagnose mycosis fungoides (MF), a type of primary cutaneous lymphoma, in the early stages of its development, due to the unspecific presentations associated with the disease. Histopathology and immunohistochemistry conduce to a more definite diagnosis. Presence of atypical T-cells in epidermis and upper dermis is the most significant pathologic finding. Herein...

In patients with colorectal cancer (CRC), the BRAF V600E mutation has been reported to be associated with several clinicopathological features and poor survival. However, the prognostic implications of BRAF V600E mutation and the associated clinicopathological characteristics in CRCs remain controversial. Therefore, we reviewed various clinicopathological features, including BRAF status, in 349...