adverse effects of antituberculosis agents such as hepatotoxicity may reduce treatment effectiveness, because they significantly contribute to nonadherence and eventually result in treatment failure, relapse or the emergence of drug resistance. garlic is an ancient herbal substance, which its effectiveness on isoniazid and rifampicin-induced hepatic injury in animal models has been demonstrated...

background & aim : dietary behavior modification has an important effect on chronic disease occurrence. this study aimed to examine the effects of an education program on nutritional knowledge, attitude, and behavior among female students studying in bojnord, iran. methods & materials : this was a clinical trial that was conducted in 2009. of all secondary schools, 2 classes were randomly selec...

conclusions our findings did not support the use of zataria multiflora boiss in premenstrual syndrome. results thirty-eight students in intervention and 37 students in placebo group completed the study. the groups had no significant difference regarding the severity of pms. both groups showed a significant improvement in pms severity score after the intervention. the repeated-measure analysis o...

background and aims. standard treatment of oral lichen planus (olp) includes topical or systemic corticosteroids that have many adverse effects. a trend toward alternative natural or herbal drugs has attended recently. this study was conducted to evaluate the effect of quercetin in treatment of erosive-atrophic olp. materials and methods. thirty patients participated in this randomized clinical...

the aim of this study was to evaluate the effects of atorvastatin on negative symptoms in patients with chronic schizophrenia. the study was a prospective, double-blind, 6-week trial. forty patients participated in the study; 19 patients were assigned to the atorvastatin group as well as 21 patients to the placebo group. for assessing negative signs, we used scale for the assessment of negative...

results the findings indicated that ucoc%/oc% was positively and significantly associated with percentage change in max force production during elbow extension (β = 0.28, p = 0.034), however, all other associations were non-significant. background muscles and bones are interconnected. recent studies suggest that undercarboxylated osteocalcin from bone may affect muscle mass and strength. there ...

introduction: palmoplantar psoriasis could hardly be differentiated from chronic tylotic eczema both clinically and histologically. the most commonly used therapeutic options for palmoplantar psoriasis are long-term therapy with topical corticosteroids and local puva. frequently, it is a recalcitrant disease. we investigated the efficacy  and tolerability of the combination of topical calcipotr...

neuroinflammation is a disorder that causes neurological disease. neuroinflammation has a significant role in induce of multiple sclerosis (ms) and one of the situations that must be treated stops the ongoing process of inflammation against the cns by self-reactive lymphocytes. according to the successful results that were obtained from the pre-clinical phase of cell therapy, many studies were ...

dna vaccination has been developed as a noteworthy immunotherapeutic approach for the battle against many serious challenges to human and animal safety, including infectious illnesses, autoimmunity, allergy and cancer. clinical trials prepare chances to examine whether dna vaccines can fulfill their final aim of demonstrating efficiency in treating humans. today, anticancer dna vaccines are qui...

randomization is an essential component of sound clinical trials which prevents selection biases and helps in blinding the allocations. randomization is a process by which subsequent subjects enrolled into trial groups only by chance which is essentially eliminates selection biases. a serious consequence of randomization is severe imbalance among treatment groups with respect to some prognostic...