Abstract A series of novel 4,6-dimorpholinyl-1,3,5-triazine derivatives 6a–6r were obtained through N -substitution and Claisen-Schmidt condensation. 1 H NMR, 13 C mass spectrometry used to characterize the molecular structures derivatives. The in vitro antiproliferation activity was evaluated using MTT assay against SW620 (human colon cancer cells), A549 nonsmall cell lung HeLa cervical MCF-7 ...

Aromatic aldehydes are efficiently condensed with 2'-hydroxyacetophenone by polymer-supported basic ionic liquid as an excellent heterogeneous catalyst utilizing the Claisen–Schmidt reaction. Microwave irradiation has been employed, providing flavanone in good yield and short reaction time.

Pyrazolines, which are nitrogen including five-membered heterocyclic structures, have been used in the organic and pharmaceutical industries. This study aimed was to synthesize characterizes new series of 3,5-diphenyl-4,5-dihydro-1H-pyrazole derivatives. The pyrazoline compounds synthesized from chalcones hydrazine hydrate two steps. In first step, were 2-amino acetophenone various substituted ...

Chalcones are the primary building blocks for flavonoids and isoflavonoids production. a three-carbon, -unsaturated carbonyl system. form when an aromatic aldehyde reacts with acetophenones in presence of catalyst. For synthesis these molecules, variety methods approaches have been reported. The Aldol condensation Claisen-Schmidt reactions most commonly referenced synthetic protocols literature...

Amorphous aluminophosphates are industrial catalysts that active in aldol-type condensations, dehydration and alkylation. The intrinsic nature of the sites present these materials is poorly understood. Herein we report a comparative investigation catalytic amorphous crystalline (AFI topology) their corresponding iron-containing analogues, employing Claisen-Schmidt condensation acetophenone benz...

Chalcones are the condensation product of acetophenone in combination with aromatic aldehydes in the presence of strong base. Chalcones and their metal complexes having prominent role in modern coordination chemistry. These compounds possessing novel structural features, interesting spectral and magnetic properties, have been the subject of intensive research due to their importance in medical,...