Background There is still controversy about the efficacy of paricalcitol in children with chronic kidney disease (CKD). Therefore, the present study was designed to assess current evidence on the efficacy of paricalcitol in CKD children. Materials and Methods <span lang="EN-...

Objective(s):MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression. They have important roles in kidney development, homeostasis and disease, and participate in the onset and progression of tubulointerstitial sclerosis and end-stage glomerular lesions that occur in various forms of chronic kidney disease (CKD). In the present study, we elucidated the role of microR...

Background: Psoriasis is a chronic and recurrent inflammatory disease that involves skin, joints and different organ systems. It is associated with Multiple morbidities such as cardiovascular disorders, diabetes, hypertension, hyperlipidemia and chronic kidney disease (CKD). Due to the high importance of the association between psoriasis and CKD which results in major side effects the aim of th...

conclusions smokers with a higher bp and/or serum ggt may be at a higher risk of developing ckd. the associations of bp and serum ggt with ckd in smokers are not entirely mediated by increased insulin resistance or chronic inflammation caused by smoking. patients and methods renal functions and cvd risk factors were assessed in middle-aged male workers. the patients were comprised of 336 nonsmo...

background this retrospective study aimed to determine the epidemiologic characteristics and risk factors of chronic kidney diseases (ckd) in patients < 18 years old at a single referral center. materials and methods in a hospital-based case control study, 66 ckd patients less than 18 years old were compared to 81 control patients (also under 18) without ckd. a patient was defined as a ckd case...

context in human beings, uric acid is the poorly soluble circulating end product of the purine nucleotide metabolism. a reduction in the glomerular filtration rate (gfr) contributes to hyperuricemia, which is frequently observed in patients with chronic kidney disease (ckd). evidence acquisition hyperuricemia is defined as a serum uric acid level > 7.0 mg/dl in males and > 6.0 mg/dl in females,...

World Kidney Day 2016 focuses on kidney disease in childhood and the antecedents of adult kidney disease that can begin in earliest childhood. Chronic kidney disease (CKD) in childhood differs from that in adults, as the largest diagnostic group among children includes congenital anomalies and inherited disorders, with glomerulopathies and kidney disease in the setting of diabetes being rela...

  Background :Attention Deficit Hyperactivity Disorder (ADHD) is the most common childhood neurological disorder. This disorder is more prevalent in some chronic diseases. The aim of this study was to investigate ADHD in children with early stages of chronic kidney disease (CKD) and to compare it with healthy children.   Methods : Seventy five 5-16-year-old children with early stages of CKD (st...