نتایج جستجو برای: cia
تعداد نتایج: 2128 فیلتر نتایج به سال:
rheumatoid arthritis is a disease associated with painful joints that affects approximately 1% of the population worldwide, and for which no effective cure is available. it is characterized by chronic joint inflammation and variable degrees of bone and cartilage erosion. oxygen metabolism has an important role in the pathogenesis of rheumatoid arthritis. reactive oxygen species (ros) are produc...
conclusion our study revealed that the hypoplastic umbilical artery group’s non-dominant cia had higher ri values than the contralateral dominant cia. results eleven of the 165 patients (6.7%) demonstrated a hypoplastic umbilical artery. second-trimester us showed median dominant and non-dominant cia pi values of 1.43 and 1.60 (p = 0.062), respectively, and median dominant and non-dominant cia ...
BACKGROUND Norepinephrine (NE), a neurotransmitter released from the sympathetic nerves, has been shown to be involved in rheumatoid arthritis (RA). However, its role in the sympathetic nervous system in RA is divergent. Herein, we demonstrate that the sympathetic neurotransmitter NE exerts an anti-inflammatory effect in collagen-induced arthritis (CIA), a mouse model of RA, by inhibiting Th17 ...
OBJECTIVE Measurement of disease-related impairment and distress is central to diagnostic, therapeutic, and health policy considerations for eating disorders across diverse populations. This study evaluates psychometric properties of a translated and adapted version of the Clinical Impairment Assessment (CIA) in an ethnic Fijian population. METHOD The adapted CIA was administered to ethnic Fi...
OBJECTIVE To examine the effect of LY309887, an inhibitor of glycinamide ribonucleotide formyltransferase in de novo purine biosynthesis on murine type collagen-induced arthritis (CIA). METHODS CIA was induced by immunization with bovine type II collagen in adjuvant. The expression of folate receptors was examined in dissected synovial tissues and bone marrow cells from arthritic and non-arth...
OBJECTIVE The aim of this study was to provide norms of Eating Disorder Examination Questionnaire (EDE-Q) and Clinical Impairment Assessment (CIA) for undergraduate women in Iran. MATERIALS AND METHODS Undergraduate women (N = 516) completed the EDE-Q, CIA, and the Binge Eating Scale (BES). RESULTS Average score, standard deviation, and percentile rank of EDE-Q and its subscale as well as C...
چکیده مقدمه: هدف از این مطالعه بررسی تأثیر شیمی درمانی های مختلف بر وقوع آمنوره ناشی از شیمی درمانی (cia) در خانم های قبل از منوپوز مبتلا به سرطان پستان در سنین مختلف می باشد. روش بررسی: این یک مطالعه پیگیری کننده بر روی 226 زن پره منوپوز مبتلا به سرطان پستان است که یکی از سه رژیم شیمی درمانی شامل: 1) روش قدیمی cmf (سیکلوفسفامید، متوترکسات، فلوئوراوراسیل) 2) شیمی درمانی بر مبنای آنتراسیکلین 3) ...
Pharmacogenomic Study of Clozapine-Induced Agranulocytosis/Granulocytopenia in a Japanese Population
BACKGROUND Clozapine-induced agranulocytosis (CIA)/clozapine-induced granulocytopenia (CIG) (CIAG) is a life-threatening event for schizophrenic subjects treated with clozapine. METHODS To examine the genetic factor for CIAG, a genome-wide pharmacogenomic analysis was conducted using 50 subjects with CIAG and 2905 control subjects. RESULTS We identified a significant association in the huma...
Epidemiological studies show an association between rheumatoid arthritis (RA) and periodontal disease. Porphyromonas gingivalis (P.gingivalis) is a well-known pathogen in periodontitis. This study investigated the pathogenic effects of P.gingivalis on autoimmune arthritis in vivo. Collagen-induced arthritis (CIA) mice were intraperitoneally injected with W83 and 2561 strains of P.gingivalis. In...
7-Amino-4-methylcoumarin (AMC) was previously shown to suppress pro-inflammatory cytokine production and prevent death in an endotoxic shock model in mice. In the present study, we investigated the effectiveness of AMC as a potential cytokine modulator in alleviating autoimmune diseases. We examined the efficacy and cytokine-modulatory activity of AMC in collagen-induced arthritis (CIA) in mice...
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