OBJECTIVE To determine whether treatment of choroidal melanoma influences survival by correlating age at death, cause of death, age at treatment, and survival predictors. DESIGN, SETTING, AND PARTICIPANTS Prospective cohort study performed at the Liverpool Ocular Oncology Centre, a supraregional, tertiary referral service in England. We included 3072 patients treated for choroidal melanoma fr...

Leukemia cell karyotypes were determined at diagnosis for 136 of 159 consecutive patients with acute lymphoblastic leukemia (ALL) who were followed for up to 35 mo. Ninety patients (67%) had abnormal karyotypes. Five chromosome categories were designated, based on the distribution of modal numbers: hyperdiploid greater than 50 (n = 41), hyperdiploid 47-50 (n = 18), pseudodiploid (n = 28), norma...

the chromosome number and type as well as karyotype in vimba vimba persa were studied. a total of 200 larvae and 10 fingerlings of this species with an average weight of 30.2g obtained from shahid ansari fish hatchery. to arrest mitosis in metaphase, larvae under study were placed in a 0.05% solution of colchicine for a period of 6h while the fingerlings were given an intramuscular injection of...

in this study, we examined the chromosome number, detailed male meiosis, microsporogenesis, pollen fertility and distribution of cytotypes of diplotaxis harra (forssk.) boiss. this is the first cytogenetic report of the taxon. the two of the populations scored now from regions of the central showed aneuploid (x = 14) meiotic chromosome count and one of the populations studied from the existed a...

Several recurrent chromosome rearrangements affecting the EVI1 locus in chromosome band 3q26 have been described in myeloid leukemia. They lead either to overexpression of this oncogene, or to the formation of EVI1 fusion transcripts.1 We employed two separate split-signal interphase fluorescent in situ hybridization (FISH) assays that facilitate the detection of 3q26 and of 3q21 rearrangements...

The present study assessed the behavior of four clones Arundo donax L. (giant reed) as a perennial rhizomatous grass increasing interest due to its high biomass production and great adaptability stress conditions. In this study, molecular, physiological, characterization was performed in greenhouse conditions on Mediterranean clones. majority physiological parameters were not significantly diff...

Chronic neutrophilic leukemia (CNL) is an infrequently encountered myeloproliferative disorder characterized by sustained neutrophilic leukocytosis, hepatosplenomegaly and the absence of the Philadelphia chromosome. This study presents a 60-year-old male patient with a diagnosis corresponding to the WHO classification criteria for CNL who was treated at the First Affiliated Hospital of Harbin M...

Intrachromosomal amplification of chromosome 21 (iAMP21) defines a distinct cytogenetic subgroup of childhood B-cell precursor acute lymphoblastic leukemia. Breakage-fusion-bridge cycles followed by chromothripsis and other complex structural rearrangements of chromosome 21 underlie the mechanism giving rise to iAMP21. Patients with iAMP21 are older (median age 9 years), with a low white cell c...